Publications by authors named "Christophe Egrot"
Introduction And Hypothesis: Managing urethral diverticula is challenging because of recurrence rate and postoperative complications. Herein, we report a standardized, single-institution experience of surgical treatment of urethral diverticula in women.
Methods: The medical record of 37 female patients treated for urethral diverticula between 2005 and 2017 in a single institution were reviewed.
Background And Objectives: We aimed to assess the feasibility and outcomes of complex ureteropelvic junction obstruction cases submitted to robotic-assisted laparoscopic pyeloplasty.
Methods: The records of 131 consecutive patients who underwent robotic-assisted laparoscopic pyeloplasty were reviewed. Of this initial population of cases, 17 were considered complex, consisting of either atypical anatomy (horseshoe kidneys in 3 patients) or previous ureteropelvic junction obstruction management (14 patients).
Purpose: To investigate the impact of 3-month androgen deprivation therapy (st-ADT) a secondary chemoprevention of indolent-localized prostate cancer (PCa).
Methods: A prospective phase II study enrolled men over 4 years with low-risk PCa and the following characteristics: PSA < 10 ng/mL, Gleason score of 6 (3 + 3) or less, three positive cores or less, and tumor stage T2a or less. Patients received a single sub-cutaneous injection of 22.
Association analysis of 9,560 prostate cancer cases from the International Consortium of Prostate Cancer Genetics confirms the role of reported prostate cancer associated SNPs for familial disease.
Hum Genet
March 2014
Previous GWAS studies have reported significant associations between various common SNPs and prostate cancer risk using cases unselected for family history. How these variants influence risk in familial prostate cancer is not well studied. Here, we analyzed 25 previously reported SNPs across 14 loci from prior prostate cancer GWAS.
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- Researchers developed a prototype using ultraviolet laser-induced autofluorescence to improve the detection of nonmuscle invasive bladder cancer, especially flat and small lesions, during cystoscopy.
- They conducted a study comparing spectroscopic results from patients with normal urothelium, papillary tumors, and flat lesions, finding significant differences in fluorescence intensity that indicate disease presence.
- The study concluded that the new imaging method accurately identifies bladder tumors with a 100% correlation to histopathological findings, demonstrating its potential as a non-invasive diagnostic tool.
Background: Detection of fusion gene TMPRSS2:ERG transcripts in urine have been recently described in order to refine urine-based detection of prostate cancer (PCa), but data its clinical impact remain scarce. We aimed at investigating the correlation of TMPRSS2:ERG, prostate cancer antigen 3 (PCA3), prostate specific antigen (PSA) density, genetic variants, and androgenic status with outcome and pathological findings at prostatic biopsy.
Methods: Between 2007 and 2011, 291 patients at risk of PCa because of PSA > 3.
Multiple prostate cancer (PCa) risk-related loci have been discovered by genome-wide association studies (GWAS) based on case-control designs. However, GWAS findings may be confounded by population stratification if cases and controls are inadvertently drawn from different genetic backgrounds. In addition, since these loci were identified in cases with predominantly sporadic disease, little is known about their relationships with hereditary prostate cancer (HPC).
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- Female urinary incontinence affects 20 to 30% of women in France, but its prevalence is under-estimated due to low consultation rates with physicians.
- With an increasing number of affected women from the "baby boom" population, there's an urgent need for better epidemiologic data and treatment options.
- Improved professional training for physicians, nurses, and physical therapists is essential to provide proper care and support for women experiencing this issue.