Epidemiology of out-of-hospital cardiac arrest: A French national incidence and mid-term survival rate study.

Out-of-hospital cardiac arrest (OHCA) is considered an important public health issue but its incidence has not been examined in France. The aim of this study is to define the incidence of OHCA in France and to compare this to other neighbouring countries. Data were extracted from the French OHCA registry.

Evolution of Survival in Cardiac Arrest with Age in Elderly Patients: Is Resuscitation a Dead End?

Background: Even if age is not considered the key prognostic factor for survival in cardiac arrest (CA), some studies question whether cardiopulmonary resuscitation (CPR) in the elderly could be futile.

Objective: The aim of this study was to describe differences in out-of-hospital CA survival rates according to age stratification based on the French National CA registry (RéAC). The second objective was to analyze the differences in resuscitation interventions according to age.

Age discrimination in out-of-hospital cardiac arrest care: a case-control study.

Background: Although some studies have questioned whether cardiopulmonary resuscitation (CPR) in older people could be futile, age is not considered an essential out-of-hospital cardiac arrest (OHCA) prognostic factor. However, in the daily clinical practice of mobile medical teams (MMTs), age seems to be an important factor affecting OHCA care.

Aims: The purpose of this study was to compare OHCA care and outcomes between young patients (<65 years old) and older patients.

[Sleep complaints and disorders in residential home patients taking hypnotic drugs].

Objective: To analyze sleep of residential home patients taking hypnotic drugs.

Patients And Method: This prospective, observational and multicentric study was performed a given day in nursing homes. Residents over than 65, having MMSE ≥ 15 and coherence A or B (for the AGGIR scale) were included.

Remifentanil discontinuation and subsequent intensive care unit-acquired infection: a cohort study.

Introduction: Recent animal studies demonstrated immunosuppressive effects of opioid withdrawal resulting in a higher risk of infection. The aim of this study was to determine the impact of remifentanil discontinuation on intensive care unit (ICU)-acquired infection.

Methods: This was a prospective observational cohort study performed in a 30-bed medical and surgical university ICU, during a one-year period.

Variations in endotracheal cuff pressure in intubated critically ill patients: prevalence and risk factors.

Background And Objective: An endotracheal cuff pressure of 20-30 cmH(2)O is recommended. Underinflation and overinflation are associated with complications such as aspiration and tracheal wall damage. The aim of this study was to identify prevalence of, and risk factors for, endotracheal cuff underinflation and overinflation.

Factors predicting bacterial involvement in severe acute exacerbations of chronic obstructive pulmonary disease.

Background: Strategies aiming at reducing antibiotic use are required in the intensive care unit (ICU). Although antibiotic treatment is recommended in patients with severe exacerbation of chronic obstructive pulmonary disease (COPD), a bacterial etiology is found in only a half of these patients.

Objectives: The aim of this study was to determine factors predicting bacterial isolation in severe acute exacerbations of COPD.

Antimicrobial treatment for ventilator-associated tracheobronchitis: a randomized, controlled, multicenter study.

Introduction: Ventilator-associated tracheobronchitis (VAT) is associated with increased duration of mechanical ventilation. We hypothesized that, in patients with VAT, antibiotic treatment would be associated with reduced duration of mechanical ventilation.

Methods: We conducted a prospective, randomized, controlled, unblinded, multicenter study.

Risk factors for relapse of ventilator-associated pneumonia related to nonfermenting Gram negative bacilli: a case-control study.

Background: The aim of this study was to determine risk factors for relapse of ventilator-associated pneumonia (VAP) related to nonfermenting Gram negative bacilli (NF-GNB).

Methods: This is a retrospective case-control study based on prospectively collected data. Two hundred and seventy six patients with monobacterial VAP related to NF-GNB were eligible.

Relationship between immunosuppression and intensive care unit-acquired multidrug-resistant bacteria: a case-control study.

Objective: To determine the relationship between immunosuppression and intensive care unit (ICU)-acquired multidrug-resistant (MDR) bacteria.

Design: Retrospective case-control study based on prospectively collected data.

Setting: A 30-bed medical and surgical ICU.

Impact of antifungal treatment on Candida-Pseudomonas interaction: a preliminary retrospective case-control study.

Objective: A pathogenic interaction between Candida albicans and Pseudomonas aeruginosa has recently been demonstrated. In addition, experimental and clinical studies identified Candida spp. tracheobronchial colonization as a risk factor for P.

Intensive care unit-acquired Stenotrophomonas maltophilia: incidence, risk factors, and outcome.

Introduction: The aim of this study was to determine incidence, risk factors, and impact on outcome of intensive care unit (ICU)-acquired Stenotrophomonas maltophilia.

Methods: This prospective observational case-control study, which was a part of a cohort study, was conducted in a 30-bed ICU during a three year period. All immunocompetent patients hospitalised >48 hours were eligible.

Multiple-drug-resistant bacteria in patients with severe acute exacerbation of chronic obstructive pulmonary disease: Prevalence, risk factors, and outcome.

Objective: To determine prevalence, risk factors, and effect on outcome of multiple-drug-resistant (MDR) bacteria in patients with severe acute exacerbation of chronic obstructive pulmonary disease.

Design: Prospective, observational, cohort study.

Setting: Thirty-bed medical intensive care unit (ICU) in a university hospital.

Impact of ventilator-associated pneumonia on outcome in patients with COPD.

Purposes: The aim of this study was to determine the impact of ventilator-associated pneumonia (VAP) on outcome in patients with COPD.

Methods: Prospective, observational, case-control study conducted in a 30-bed ICU during a 5-year period. All COPD patients who required intubation and mechanical ventilation (MV) for > 48 h were eligible.

Effect of gingival and dental plaque antiseptic decontamination on nosocomial infections acquired in the intensive care unit: a double-blind placebo-controlled multicenter study.

Objective: To document the effect of gingival and dental plaque antiseptic decontamination on the rate of nosocomial bacteremias and respiratory infections acquired in the intensive care unit (ICU).

Design: Prospective, multicenter, double-blind, placebo-controlled efficacy study.

Setting: Six ICUs: three in university hospitals and three in general hospitals.

Effect of ventilator-associated tracheobronchitis on outcome in patients without chronic respiratory failure: a case-control study.

Introduction: Our objective was to determine the effect of ventilator-associated tracheobronchitis (VAT) on outcome in patients without chronic respiratory failure.

Methods: This was a retrospective observational matched study, conducted in a 30-bed intensive care unit (ICU). All immunocompetent, nontrauma, ventilated patients without chronic respiratory failure admitted over a 6.

First-generation fluoroquinolone use and subsequent emergence of multiple drug-resistant bacteria in the intensive care unit.

Objective: The objective of this study was to determine the relationship between fluoroquinolone (FQ) use and subsequent emergence of multiple drug-resistant bacteria (MRB) in the intensive care unit (ICU).

Design: The authors conducted a prospective observational cohort study and a case control study.

Setting: The study was conducted in a 30-bed ICU.

Antiphospholipid antibodies and the risk of thromboembolic events in valvular heart disease.

Objective: To investigate the role of antiphospholipid antibodies (aPLs) in subsequent thromboembolic events and mortality in a prospective follow-up of 89 patients with severe, nonspecific valvular heart disease.

Patients And Methods: Between November 1, 1993, and March 31, 1994, 89 patients with valvular heart disease were assessed for the presence of anticardiolipin antibodies and lupus anticoagulant. The primary end point was thromboembolic events, and the secondary end points were cardiovascular mortality and overall mortality.