Publications by authors named "Christophe Benvenuti"
Background: Transcatheter aortic valve implantation (TAVI) has become a first-line therapeutic option in patients with severe, symptomatic aortic stenosis at increased surgical risk. Despite its success, the TAVI procedure has been associated with acute life-threatening complications as myocardial infarction secondary to periprocedural coronary occlusion, annular rupture, or vascular injury.
Case Summary: A 79-year-old woman with a dysfunctional bioprosthetic valve following previous surgical valve replacement was hospitalized in our institution to perform a Valve-in-Valve Transcatheter Aortic Valve Replacement (ViV TAVR).
Prevalence, clinical characteristics and outcomes of high-risk patients treated for severe aortic stenosis prior to and after transcatheter aortic valve implantation availability.
Eur J Cardiothorac Surg
May 2015
Article Synopsis
- TAVI has become a popular treatment option for high-risk patients with severe aortic stenosis, and this study compared outcomes before and after its availability in a surgical institution.
- The prevalence of high-risk patients increased significantly after TAVI was introduced, with 89% of these patients receiving TAVI in the modern era, whereas fewer received it before.
- Although high-risk patients are now older and present with more advanced symptoms, their one-year survival rates are similar across both eras, indicating TAVI's impact but not necessarily improved survival outcomes within the first year.
Background And Aim Of The Study: Because valve replacement for aortic stenosis (AS) remains a difficult surgical challenge in the presence of left ventricular dysfunction, the immediate and long-term outcomes, and evolution of left ventricular ejection fraction (LVEF) in this setting, were analyzed.
Methods: Forty-three consecutive patients with severe AS (valve area < or =1 cm2) and reduced LVEF (< or =40%) who underwent valve replacement surgery at the authors' institution between April 1998 and December 2003 and were studied retrospectively.
Results: Preoperative characteristics included: LVEF 33 +/- 6%, mean transaortic pressure gradient 46 +/- 13 mmHg, and aortic valve area 0.