Histomorphology and grading of regression in gastric carcinoma treated with neoadjuvant chemotherapy.

Background: Neoadjuvant chemotherapy has shown some success in the treatment of gastric carcinoma, but objective parameters for measuring its effects are lacking. The authors performed the current study to determine which histomorphologic features are correlated with patient prognosis after chemotherapy.

Methods: Thirty-six patients with gastric carcinoma were treated with a combination of etoposide, doxorubicin, and cisplatin.