Publications by authors named "Christoph Hofstadler"
Front Pharmacol
July 2017
Article Synopsis
- Metabolic diseases like obesity and type 2 diabetes are on the rise, prompting research into the bile acid receptor TGR5, which plays a key role in regulating metabolism and promoting hormone secretion in the intestine.
- The study aimed to find plant extracts that activate TGR5, isolate their effective components, and examine how gut bacteria might alter these components’ activity.
- Results showed that extracts from certain spices significantly increased TGR5 activity, with specific triterpene acids identified as the main active ingredients, demonstrating a clear link between these compounds and their effect on TGR5.
