Publications by authors named "Christoph Hoffmann"

In agricultural landscapes, the removal of semi-natural habitats (SNH) and the intensive use of pesticides contribute to declines of biodiversity, including crop pollinators such as bees (Hymenoptera: Apoidea). However, effects of pesticide use and landscape characteristics on bees have rarely been studied together. In this study, we investigated how SNH in the surrounding landscape, organic and conventional management, and the reduction of fungicides affect wild bee diversity in 32 vineyards in southwest Germany.

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Risk assessments of chemical pesticides toward natural enemies are crucial for ensuring sustainable grapevine-integrated pest management. In this context, laboratory experiments were conducted to evaluate the toxicity of four insecticides (lambda-cyhalothrin, flupyradifurone, acetamiprid, and cyantraniliprole) and one fungicide (spiroxamine) commonly applied in German (European) vineyards on the pupae and adults of both , a parasitoid of the vine mealybug , and , a parasitoid of the European grapevine moth, . The tested pesticides did not significantly affect the development of the pupal stage inside mealybug mummies or the emergence of the parasitoid .

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Academic training, especially at the undergraduate level, is a marginal topic in science studies today. Scientific practices have commonly been approached through studies of research contexts-most visibly, the lab-and only sporadically through studies of the classroom or other teaching contexts. In this article, we draw attention to the pivotal role that academic training plays in the formation and reproduction of thought collectives.

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Background: Pesticides are considered main contributors to global arthropod declines and therefore may decrease the provision of ecosystem services such as natural pest control. Organic farming and cultivating pest- and disease-resistant varieties can allow pesticide applications and their impacts on nontarget organisms and the environment to be reduced. We investigated the effects of organic versus conventional management and fungus-resistant versus susceptible wine grape varieties on arthropod biodiversity and pest control of grape berry moths in 32 vineyards in the Palatinate region, Germany.

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The aim of this study was to determine whether early surgical treatment results in better neurological recovery 12 months after injury than late surgical treatment in patients with acute traumatic spinal cord injury (tSCI). Patients with tSCI requiring surgical spinal decompression presenting to 17 centres in Europe were recruited. Depending on the timing of decompression, patients were divided into early (≤ 12 hours after injury) and late (> 12 hours and < 14 days after injury) groups.

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Article Synopsis
  • Insulin resistance in the brain negatively impacts weight maintenance and fat distribution, and there is limited understanding of how to restore brain insulin sensitivity in humans.
  • This study involved an 8-week supervised aerobic exercise program for 21 overweight and obese participants, using functional MRI to measure changes in brain insulin sensitivity before and after the intervention.
  • Results showed that regular exercise improved brain insulin action similar to that of healthy individuals, leading to better metabolism, reduced visceral fat, decreased hunger, and enhanced cognitive function, indicating that exercise can be a potential treatment for brain insulin resistance.
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Metabarcoding is a powerful tool for ecological studies and monitoring that might provide a solution to the time-consuming taxonomic identification of the vast diversity of insects. Here, we assess how ambient weather conditions during Malaise trap exposure and the effort of trapping affect biomass and taxa richness in vineyards. Biomass varied by more than twofold with weather conditions.

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Physical training improves insulin sensitivity and can prevent type 2 diabetes (T2D). However, approximately 20% of individuals lack a beneficial outcome in glycemic control. TGF-β, identified as a possible upstream regulator involved in this low response, is also a potent regulator of microRNAs (miRNAs).

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Article Synopsis
  • Scientists studied how exercise affects liver mitochondria when mice eat a lot of high-calorie food.
  • They found that exercise helped improve how mitochondria work, preventing problems like fatty liver disease.
  • Overall, exercising while eating high-energy diets was better for the mice's liver and muscles, helping them stay healthier.
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Plants release volatiles in response to caterpillar feeding. These herbivore-induced plant volatiles (HIPVs) attract natural enemies of the herbivores and repel or attract conspecific adult herbivores in a tri-trophic interaction which has been considered to be an indirect plant defense against herbivores. Recently, we demonstrated the attraction of male and female European grapevine moth, Lobesia botrana (Denis & Schiffermüller) (Lepidoptera: Tortricidae) to a blend of phenylacetonitrile and acetic acid, two compounds identified as HIPVs in heterospecific apple-leafroller interactions.

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Habitat simplification and intensive use of pesticides are main drivers of global arthropod declines and are, thus, decreasing natural pest control. Organic farming, complex landscapes, and local vineyard management practices such as implementation of flower-rich cover-crop mixtures may be a promising approach to enhance predator abundance and, therefore, natural pest control. We examined the effect of organic versus integrated management, cover-crop diversity in the vineyard inter-rows, and landscape composition on the natural pest control of eggs and pupae.

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Viticultural practices and landscape composition are the main drivers influencing biological pest control in vineyards. Predatory mites, mainly phytoseiid (Phytoseiidae) and tydeoid mites (Tydeidae), are important to control phytophagous mites (Tetranychidae and Eriophyidae) on vines. In the absence of arthropod prey, pollen is an important food source for predatory mites.

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Purpose: This study aimed to compare clinical results and fusion rates of uncoated polyetheretherketone (PEEK) cages with titanium-coated PEEK cages in posterior lumbar interbody fusion (PLIF) surgery.

Methods: A prospective randomised study including 60 patients with one- or two-segment lumbar degenerative diseases. Patients received either titanium-coated PEEK cages (group A) or uncoated PEEK cages (group B).

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Context: Exercise training improves glycemic control and increases mitochondrial content and respiration capacity in skeletal muscle. Rodent studies suggest that training increases mitochondrial respiration in adipose tissue.

Objective: To assess the effects of endurance training on respiratory capacities of human skeletal muscle and abdominal subcutaneous adipose tissue and to study the correlation with improvement in insulin sensitivity.

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The identification of volatile organic compounds (VOCs) leading to short-range attraction and oviposition of the European grapevine moth and European grape berry moth (Lepidoptera: Tortricidae) is crucial in order to establish bait-based decision support systems for control of these pests. Therefore, we developed a method to measure the real-time behavioral response of female moths to VOCs using a four-chamber olfactometer coupled with a video tracking system. Ten synthetic VOCs were selected for this study: ()-(-)-perillaldehyde, ()/()-linalool oxide, (±)-limonene, linalool, ()-β-caryophyllene, α/β-farnesene, (-)-α-cedrene, methyl salicylate and cumene.

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Mitochondria are dynamic organelles with diverse functions in tissues such as liver and skeletal muscle. To unravel the mitochondrial contribution to tissue-specific physiology, we performed a systematic comparison of the mitochondrial proteome and lipidome of mice and assessed the consequences hereof for respiration. Liver and skeletal muscle mitochondrial protein composition was studied by data-independent ultra-high-performance (UHP)LC-MS/MS-proteomics, and lipid profiles were compared by UHPLC-MS/MS lipidomics.

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Over the last decade, Matsumura, an invasive pest of soft-skinned fruits, gradually established itself in Europe, often resulting in significant economic losses. In 2011, when was first described for Germany, the Julius Kühn Institut (JKI) started a monitoring program in southwest Germany to study the occurrence and activity of the fly. Capture data from late 2011⁻early 2018 from 100 traps were analyzed for the effect of weather and immediate habitat on trap captures at different times of the year.

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Measuring mitochondrial respiration in cultured cells is a valuable tool to investigate the influence of physiological and disease-related factors on cellular metabolism; however, the details of the experimental workflow greatly influence the informative value of the results. Working with primary cells and cell types capable of differentiation can be particularly challenging. We present a streamlined workflow optimised for investigation of primary human skeletal muscle cells.

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Greencover crops are widely recommended to provide predators and parasitoids with floral resources for improved pest control. We studied parasitism and predation of European grapevine moth () eggs and pupae as well as predatory mite abundances in an experimental vineyard with either one or two sowings of greencover crops compared to spontaneous vegetation. The co-occurrence between greencover flowering time and parasitoid activity differed greatly between the two study years.

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Objective: Angiopoietin-like protein-4 (ANGPTL4) is a circulating protein that is highly expressed in liver and implicated in regulation of plasma triglyceride levels. Systemic ANGPTL4 increases during prolonged fasting and is suggested to be secreted from skeletal muscle following exercise.

Methods: We investigated the origin of exercise-induced ANGPTL4 in humans by measuring the arterial-to-venous difference over the leg and the hepato-splanchnic bed during an acute bout of exercise.

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