Remodelling intravitreal therapy pathways for macular disease during the COVID-19 pandemic and an Austrian national lockdown.

Objective: To analyse the remodelling and recovery of a relocated intravitreal injection (IVI) service with an adapted treatment regimen in a tertiary referral centre during a nationwide lockdown with initial cancellation of all non-emergency treatments caused by the COVID-19 pandemic.

Methods And Analysis: For this retrospective observational study at Hanusch Hospital, Vienna, between 16 March 2020 and 5 May 2020, we conducted an analysis of an appointment booking system based on prioritisation incorporating disease class, severity and fellow eye status by evidence-based impact on irreversible structural impairment and survey data from telephone interviews. Recapture time was defined as the time-to-discard the backlog of patients in need for treatment.

Effect of Subfoveal and Extrafoveal Hyporeflective Zones due to Iatrogenic Traction during Membrane Peeling for Epiretinal Membranes on Postoperative Outcomes.

Purpose: The aim of our study using an intraoperative optical coherence tomography (iOCT) device was to assess the rate of neurosensory elevation with resulting subfoveal and extrafoveal hyporeflective zones during membrane peeling and to evaluate a possible influence on postoperative outcomes.

Procedures: This study included patients scheduled for pars plana vitrectomy with membrane peeling due to idiopathic epiretinal membrane. All patients underwent 23-G pars plana vitrectomy with iOCT-guided membrane peeling and were scheduled for follow-up examinations at 1 day, 5 days, and 3 months after surgery.

Risk factors for postoperative intraretinal cystoid changes after peeling of idiopathic epiretinal membranes among patients randomized for balanced salt solution and air-tamponade.

Purpose: Epiretinal membranes (ERM) are macular disorders leading to loss of vision and metamorphopsia. Vitrectomy with membrane peeling displays the gold standard of care. Aim of this study was to assess risk factors for postoperative intraretinal cystoid changes in a study population randomized for balanced salt solution and air-tamponade at the end of surgery.

Diagnostic precision of a microscope-integrated intraoperative OCT device in patients with epiretinal membranes.

Purpose: Preoperative and postoperative optical coherence tomography (OCT) of macular pathologies can be regarded as the gold standard diagnostic technique, providing detailed information on the microstructures of the macula for planning the surgical procedure and comparing improvements after surgery in the follow-up period. Intraoperative use of OCT is a novel application to support surgeons during macular surgery. The aim of this study was to examine the diagnostic precision of a microscope-integrated intraoperative spectral-domain OCT (i-OCT) device and compare imaging results to a stand-alone spectral-domain OCT (SD-OCT) device.

Visualizing Macular Structures During Membrane Peeling Surgery With an Intraoperative Spectral-Domain Optical Coherence Tomography Device.

Background And Objective: The aim of this study was to examine the quality of intraoperative visualization of the posterior hyaloid, epiretinal membrane (ERM), inner limiting membrane (ILM), and hyporeflective subfoveal zone with a commercially available, microscope-integrated spectral-domain OCT setup (mi-SD-OCT) (Rescan 700; Carl Zeiss Meditec AG, Germany).

Patients And Methods: Twenty patients prospectively scheduled for pars plana vitrectomy with membrane peeling due to an idiopathic ERM were included. Standard 23-gauge, three-port pars plana vitrectomy with membrane peeling and staining of the ERM with a trypan blue-based chromovitrectomy dye was performed in all cases.

Eplerenone in patients with chronic recurring central serous chorioretinopathy.

Purpose: To evaluate the effect of eplerenone on patients with long-term recurring central serous chorioretinopathy (CSC).

Methods: In this retrospective case series, 11 patients with chronic recurring CSC were included. The main focus was to include patients who had undergone photodynamic therapy (4 patients), had undergone anti-vascular endothelial growth factor treatment (3 patients), or had several episodes of CSC in the past (4 patients) (mean age 60 years; SD 9.

Predicting Lens Diameter: Ocular Biometry With High-Resolution MRI.

Purpose: The aim of this study was to correlate different biometric dimensions of the eye as measured from ocular magnetic resonance imaging (MRI) scans to predict the lens diameter.

Methods: High-resolution ocular MRI scans of 100 eyes of 100 patients were reviewed. Various anatomical variables of the eye such as the axial length, the globe diameter, and the lens dimensions were measured.

Proton beam radiotherapy of diffuse iris melanoma in 54 patients.

Background: Treatment modalities in iris melanoma include excision, plaque radiotherapy, photon or proton beam therapy and enucleation. In extensive tumours and diffuse seeding, radiotherapy remains as an alternative to enucleation.

Methods: This study is a retrospective, consecutive, interventional, single-institutional case series.

Comments on "Backpropagation algorithms for a broad class of dynamic networks".

In a recent paper, De Jesús proposed a general framework for describing dynamic neural networks. Gradient and Jacobian calculations were discussed based on backpropagation-through-time (BPTT) algorithm and real-time recurrent learning (RTRL). Some errors in the paper of De Jesús bring difficulties for other researchers who want to implement the algorithms.