Internal standard application to dried blood spots by spraying: investigation of the internal standard distribution.

Background: The scientifically and logistically best way of application of the internal standard (IS) in the analysis of dried blood spots (DBS) analysis is still a matter of debate and investigation. Most commonly the IS is added in the solvent used for extraction of the discs punched from DBS. In this case, the recovery of the non-extracted IS is complete while the recovery of the analyte extracted from DBS is different from the IS.

How close does an uncemented hip stem match the final rasp position?

During total hip arthroplasty the final clinical position of the cementless CLS stem (Centerpulse) is not always identical to the position of the final rasp with which a successful trial reduction was performed. Therefore, the rasp-stem correspondence of CLS system (Centerpulse) was investigated in a laboratory study and compared to the CBC-T system (Mathys). Both systems showed an average rasp-stem mismatch below 2 mm in three orthogonal directions.

Femoroplasty-augmentation of mechanical properties in the osteoporotic proximal femur: a biomechanical investigation of PMMA reinforcement in cadaver bones.

Objective: To determine the feasibility of polymethyl-methacrylate injection into the osteoporotic proximal femur and its effect on the mechanical properties.

Design: In vitro pairwise comparison of non reinforced and reinforced bones in a load to failure loading mode.

Background: Hip fractures represent an important public healthcare problem.