[Cat-scratch disease associated with osteomyelitis].

A case of cat-scratch disease in an 8 year-old girl is reported. The inoculation injury followed by regional lymphadenopathy was typical of Parinaud syndrome. This patient also had vertebral lesions on scintigraphy, x-rays and CT scan.

[Multicenter study of the activity of pefloxacin on bacteria isolated in a hospital milieu].

Minimal inhibitory concentrations (MICs) of pefloxacin were evaluated by agar dilution for 3422 bacterial strains isolated in nine hospitals. Enterobacteriaceae proved very sensitive to pefloxacin: 62 p. 100 of 1743 strains tested had MIC less than or equal to 0.

Detection of IgG antibodies to lymphadenopathy-associated virus in patients with AIDS or lymphadenopathy syndrome.

IgG antibodies to lymphadenopathy-associated virus ( LAV ) were found by a specific enzyme-linked immunosorbent assay in 18/48 (37.5%), patients with acquired immunodeficiency syndrome, 38/51 (74.5%) patients with lymphadenopathy syndrome, 8/44 (18%) homosexual men without lymphadenopathy, and 1/100 unselected blood donors.

Epidemiological features of Legionnaires' disease in the Paris area.

Although the first French case of Legionnaires' disease (LD) was diagnosed in 1979 and the first six serogroups of L. pneumophila and L. longbeachae serogroup 2 were demonstrated in environmental samples from the Paris area, the incidence of the disease has not yet been evaluated in France.

[In vitro activity of cefatiolene (RP 42,980) against hospital bacteria. Comparison with cefotaxime and lamoxactam. Results of a multicenter study].

This work reports a multicenter study of antibacterial activity of cefatiolene (RP 42 980), a new third generation cephalosporin, in comparison with cefotaxime and lamoxactam. On the basis of MIC, activity of the three products is similar or Gram negative rods, but cefotaxime is a little more active on Enterobacteriaceae. The activity against Staphylococci requires further studies, indeed the determination of IC 50 of some strains showed a better activity of cefatiolene, but this was not observed by determination of MIC.

Phospholipase activities of bronchoalveolar lavage fluid in rat Pneumocystis carinii pneumonia.

Respiratory distress, main clinical symptom of P. carinii pneumonia, is unexplained. We wondered if it could be linked with a lung surfactant anomaly.

[Sensitivity to mezlocillin Gram-negative aerobic bacilli according to their pattern of resistance to the usual beta-lactam antibiotics (author's transl)].

Gram-negative aerobic bacilli (Enterobacteria, Pseudomonas, Acinetobacter) isolated in clinical circumstances at the microbiology of the Claude Bernard Hospital, Paris, are classified according to their resistance to the usual beta-lactam antibiotics routinely tested: ampicillin, carbenicillin, cefalotin. The MICs of mezlocillin were measured on 204 strains and compared to the results obtained with older drugs in each group.

[Bacteria seen in acute otitis media in children hospitalised for infectious diseases].

The authors draw the following conclusion on the basis of 85 cases of children hospitalised for infectious diseases : -amongst childhood infectious diseases, measles between the ages of 7 and 14 is most commonly associated with complications in the form of otitis (50 as against 19 other diseases). -Staphylococcus aureus was the dominant organism in measles otitis, but in addition to a particular affinity of this organism for measles, it is also necessary to bear in mind contamination by hospital flora, amongst which staphylococci are especially representative, in view of the late development of the otitis and the multiresistance of staphylococci isolated after the 4th day of admission. -Bacteria seen in other exanthematous fevers were more varied but if there is not rapid cure of the otitis, the generally sensitive flora is replaced by a multiresistant hospital flora, once again dominated by staphylococcus aureus and Gram negative bacilli.

[Benign inoculation lymphoreticulosis or cat-scratch disease].

Discovered in 1950-51 by two great parisian medical teams, inoculation lymphoreticulosis, also called cat's scratch disease, is locoregional adenitis whose aetiology is imperfectly determined. Following, often bu not always, cat's scratch, it may evolve to suppuration. Pus is always aseptic.

[Anatomic and bacteriological study of surgically extracted valves in patients with bacterial endocarditis].

We studied 64 cases of bacterial endocarditis which required heart surgery for hemodynamic defects and/or failure of the antibiotic therapy. We performed a bacteriologic and histologic investigation of the removed valves. The organisms were evidenced through culture and specific stainings.

[Morphological diagnosis of Pneumocystis carinii].

Pneumocystis carinii pneumonia can only be diagnosed once the microorganism is demonstrated. The authors review and illustrate various staining technics, and discuss for each of them specific advantages. All samples must by systematically examined both by phase contrast microscopy and by light microscopy after Gomori-Grocott and Gram-Weigert stains.

[Anatomo-clinical and experimental studies on pneumocystis carinii. Preliminary note].

The authors have been interested over the last year in the detection of pneumocystis carinii in patients with immune deficiencies, whether natural or artificial. After a brief historical and general introduction, they discuss their procedures, the pathological substances available, the staining techniques and the examination of autopsy specimens. They undertook experimental work on this micro-organism, e.