[Constitutional painful callosities. Analgesic efficacy of etretinate].

We have recently evaluated eight patients with an unusual genetic dermatosis that was characterized by the development of painful callosities at pressure points of soles, with tender yellowish-brown hyperkeratosis. These lesions are very painful: walking produced pain that was severe. The patients performing manual labor, in addition, had multiple callosities on the palms.

[Eruptive generalized syringomas, milium and atrophoderma vermiculata. Nicolau and Balus' syndrome (author's transl)].

It appears justified to isolate under the term syndrome of Nicolau and Balus', a group of deformities that include eruptive syringomas of the disseminated micropapular type, milium cysts and atrophoderma vermiculata. We present here a highly typical observation of an 11-year-old child whose mother also presented with eruptive syringomas. This syndrome accentuates the semiological value of disseminated syringomas and atrophoderma vermiculata, which often occur in the context of a complex syndrome.

[Pachyonychia congenita. Three familial cases. Effects of the treatment by aromatic retinoid (RO 10.9359) (author's transl)].

The authors present three familial cases of Schonfeld's type I pachyonychia. This syndrome represents the association of pachyonychia with palmoplantar keratodermia, frictionnal keratosis and bullae, hyperidrosis, oral leucokeratosis. This genotype is present in the remaining family.

[Atopic dermatitis and pox-virus superinfections (author's transl)].

Subjects afflicted with atopic dermatitis are particularly predisposed to such viral superinfections as verruca, herpes (eczema herpeticum) and vaccinia (eczema vaccinatum). Knowledge of superinfection by the molluscum contagiosum virus is more recent and the authors describe one case. The orf virus (responsible for ovine ecthyma contagiosum), however, has never been described as responsible for the profuse superinfection of an atopic eczema.

[Idiopathic eruptive macular pigmentation following pityriasis rosea. Presentation of two cases (author's transl)].

We describe two cases of acquired hyperpigmented macular eruption following pityriasis rosea. This condition is characterized by an eruption of discrete grayish macules on the trunk. On the back, the lesion are oval and their long axis follows the cutaneous liners.

Vitamin B-12 induced acnes.

A type of acne induced by vitamin B-12 deserves a special place among acneiform eruptions. The eruption is monomorphic and of a particular type. It consists of voluminous folliculitis lesions which develop acutely after the first injections of vitamin B-12 and disappear rapidly when treatment is discontinued.

[Acne-like eruption induced by pseudo-xanthoma elasticum (author's transl)].

Pseudoxanthoma elasticum can induce acne-like eruption. The lesions are located on the latero-cervical parts and consist of comedones, cysts and inflammatory nodules. Histologically, there are no transepithelial eliminations or follicultitis, but a very important granulomatosus tissue with epithelioid cells and a giganto-cellular reaction with elastotic fibres phagocytosis.

Chequered localized pseudoxanthoma elasticum: a variety of Christensen's exogenous pseudoxanthoma elasticum?

We report a very curious case of a condition which has never been described before. Its features are comparable but not quite identical with those of Christensen's saltpetre-induced PXE which the author considers to be an exogenous variety of pseudoxanthoma elasticum. Since our case appeared spontaneously without any accidental episode we prefer to designate it under the name 'localized PXE'.

Cockade-like vitiligo and linear vitiligo a variant of fitzpatrick's trichrome vitiligo.

The authors report 2 cases of atypical vitiligo in which they observed 1) "cockade-like" lesions resembling those of "trichrome" vitiligo (from the centre to the periphery, achromic area, hypochromic ring, normal or hyperchromic border), 2) numerous linear achromic lesions corresponding to former excoriations (Koebner's phenomenon, isomorphic phenomenon). Related affections are discussed with reference to these cases; the trichrome vitiligo described by Lerner and Fitzpatrick, and the primary leukomelanodermas described in black patients by Basset and by Sarrat and Nouhouayi.

[Lamprene (Clofazimine) treatment of chronic lupus erythematoides (author's transl)].

Lamprene (Clofazimine) was administered over a period of three months, at a dose of 100 mg to 200 mg per day, to six patients with chronic lupus erythematosus. Remission was observed in these six cases, without any side-effect.

[Vertical striated sand-papered twenty-nail dystrophy (author's transl)].

Vertical striated sand-papered twenty-nail dystrophy, an entity observed in both children and adults, is suggestive of an expression of alopecia areata. When the vertical striated sand-papered effect is not uniformly distributed over the full surface of the nail plates the disorder may be caused by lichen planus.

[Acquired fibro-keratoma. Report of 8 cases].

The acquired fibro-keratoma is a benign fibro-epithelial tumor of acquired nature. I was set apart as a distinct entity in 1968 by Bart et al. who named it "acquired digital fibro-keratoma".