Publications by authors named "Christoforos Asproudis"
Pregnancy induces a cascade of hemodynamic changes that are likely to affect the maternal systemic and ocular circulation. The current study aimed to investigate retinal microvasculature alterations in women with preterm and full-term pregnancy using optical coherence tomography angiography (OCT-A). This was a cross-sectional, comparative, single-center study.
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- The study aimed to examine the microcirculation characteristics in the inner retinal layers of patients with early-stage Parkinson's disease (PD) using Optical Coherence Tomography Angiography (OCT-A).
- Involving 32 PD patients and 46 healthy controls, the results showed that PD patients had significantly lower vessel density and perfusion in specific retinal areas compared to controls, while foveal vessel density was higher but not significantly so.
- The findings suggest that OCT-A imaging could serve as a valuable tool for detecting changes in retinal microcirculation, possibly aiding in the early diagnosis of Parkinson's disease.
Purpose: The retina may provide a window to estimate systemic vascular status; therefore, there has been interest in identifying microcirculation characteristics that possibly reflect hypoxic alterations in obstructive sleep apnea/hypopnea syndrome (OSAS). Emerging evidence has suggested that retinal microvasculature investigation holds the potential to characterize the pathophysiology involved in ocular manifestations of OSAS. The advent of optical coherence tomography angiography (OCT-A) has attracted significant attention as this technique offers detailed analysis of the retinal capillary plexus.
View Article and Find Full Text PDFPurpose: Given the fact that retina may provide a window into the central nervous system, there has been interest in identifying retinal biomarkers as predicting factors of pathological processes in neurodegenerative disorders. Emerging evidence has suggested that macular microcirculation changes in Parkinson disease (PD) may indicate the alterations of cerebral microvasculature. The use of Optical Coherence Tomography Angiography (OCT-A) has attracted significant attention in recent years as this technique offers a detailed analysis of the existence of changes at the macular capillary plexus.
View Article and Find Full Text PDFPurpose: The purpose of this review is to provide an update on ophthalmological manifestations of Noonan Syndrome (NS). Emerging evidence has suggested that NS patients may present with a wide spectrum of ocular characteristics. Detailed investigation of genotype has revealed the diversity of related gene mutations.
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