Characterization of shape memory polymer foam hemostats in in vitro hemorrhagic wound models.

Shape memory polymer foam hemostats are a promising option for future hemorrhage control in battlefield wounds. To enable their use as hemostatic devices, they must be optimized in terms of formulation and architecture, and their safety and efficacy must be characterized in animal models. Relevant in vitro models can be used for device optimization to help mitigate the excess use of animals and reduce costs of clinical translation.

Long-term follow-up of patients with serpinginous choroiditis.

Purpose: To evaluate the long-term clinical course of serpiginous choroiditis-a recurrent inflammatory disease that causes progressive visual loss-and to determine the efficacy of immunosuppressive therapy.

Methods: A retrospective study of patients who met inclusion criteria for serpiginous choroiditis at The University of Iowa Hospitals and Clinics was performed. Information collected included duration of follow-up, number of recurrences of inflammation, visual acuities, and development of choroidal neovascularization.

Birdshot retinochoroiditis: long term follow-up of a chronically progressive disease.

Purpose: To determine the long-term course of birdshot retinochoroiditis by reviewing patient records from The University of Iowa Hospitals and Clinics.

Design: A descriptive case series.

Methods: We conducted a retrospective review of 19 patients seen at The University of Iowa for birdshot retinochoroiditis.

Evaluation of efficacy and complications: primary pediatric orbital implants after enucleation.

Background: Orbital implants are used routinely in pediatric patients at the time of enucleation. Complications, such as exposure, ptosis, and infection, may occur after implantation. Controversy continues regarding the rate of complications with newer implants in the pediatric population.

Reopening of macular holes after initially successful repair.

Objective: To evaluate the frequency and prognosis of reopening of a macular hole after initially successful repair in a defined patient cohort.

Design: Retrospective consecutive noncomparative case series.

Participants: Seventeen cases of reopened macular holes among 390 cases of idiopathic macular holes that previously had undergone macular hole surgery were studied.

Intraorbital implants after enucleation and their complications: a 10-year review.

Background: Many different types of orbital implants have been used after enucleation. Associated complications such as infection, exposure, extrusion, and ptosis have been reported.

Objective: To describe 342 consecutive patients who underwent enucleation with intraorbital implant placement at the Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, Fla, during the past 10.

Vitrectomy and systemic fluconazole for treatment of endogenous fungal endophthalmitis.

Background And Objective: To investigate the efficacy of pars plana vitrectomy and oral fluconazole without injection of intravitreal antimycotic agents in the treatment of vitritis resulting from Candida endophthalmitis.

Patients And Methods: Six eyes of five patients with suspected Candida endophthalmitis were treated with pars plana vitrectomy and systemic fluconazole for at least 3 weeks. Patients were observed postoperatively for at least 4 months.

Treatment of retinal breaks with autologous serum in an experimental model.

Purpose: The standard treatment for retinal breaks is thermal adhesion. Breaks in the posterior pole (i.e.

Secondary optic nerve tumors.

Secondary tumors of the optic nerve are more common than primary optic nerve tumors. The involvement of the optic nerve may arise from direct invasion from intraocular malignancies, from hematopoietic malignancy, from meningeal carcinomatosis, or from distant primary tumors. Orbital tumors rarely invade the optic nerve, and brain tumors involve it only in their late stages.