Effects of sertraline in the prevention of low blood pressure in patients undergoing hemodialysis.

Introduction: Intradialytic hypotension (IDH) is a major complication of hemodialysis, with a prevalence of about 25% during hemodialysis sessions, causing increased morbidity and mortality.

Objective: To study the effects of sertraline to prevent IDH in hemodialysis patients.

Methods: This was a double-blind, crossover clinical trial comparing the use of sertraline versus placebo to reduce intradialytic hypotension.