Publications by authors named "Christine Younan"

Article Synopsis
  • Biologics like adalimumab are being increasingly used to treat systemic uveitis, aiming to improve patient outcomes in vision preservation.
  • A study involving 46 patients showed that most were able to discontinue or significantly reduce their corticosteroid use while effectively managing their uveitis.
  • Results indicated that most patients maintained or improved their vision over an average follow-up of about 4.5 years, with a low relapse rate and no serious side effects reported.
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Purpose: We compared early age-related macular degeneration (AMD) lesion characteristics between white Australians and Singaporean Asians.

Methods: Participants of the Blue Mountains Eye Study (BMES; whites, n = 3508) and the Singapore Epidemiology of Eye Disease Study (SEED; Malay, n = 3280, Indian, n = 3400, and Chinese, n = 3353) underwent examinations, including retinal photography. The AMD lesions were assessed following the Wisconsin AMD grading protocol by the same photographic grader.

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Background: To examine the prevalence of serpiginous choroidopathy in a predominantly Caucasian community, to examine associations between serpiginous choroiditis and other systemic diseases, and to report on the effect of immunosuppression on the long-term course of serpiginous choroiditis.

Design: Retrospective cohort study with patients from tertiary care centres and private practices.

Participants: 18 patients, mean age 48 years at baseline.

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Background: Health of migrants is a major public health challenge faced by governments and policy makers. Asian Indians are among the fastest growing migration groups across Asia and the world, but the impact of migration and acculturation on diabetes and diabetes-related eye complications among Indians living in urban Asia remains unclear.

Methodologies/principal Findings: We evaluated the influence of migration and acculturation (i.

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Purpose: To describe the prevalence of epiretinal membrane (ERM) and its risk factors in an Indian population and compare the findings with other populations.

Methods: The Singapore Indian Eye Study is a population-based survey of 3400 Asian Indians aged between 40 and 80 years. A comprehensive ophthalmic examination, standardized interviews, and laboratory blood tests were performed.

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Purpose: To assess the association between smoking and the long-term incidence of cataract and cataract surgery.

Methods: In a population-based cohort of Australians aged 49 years and over, 3654 participants were seen at baseline (1992-94) and 2406 were seen after 5- and/or 10-years and had photographs taken to assess incident cataract. Smoking status was recorded at interview.

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Purpose: To assess whether an association exists between cardiovascular disease, vascular risk factors and incident cataract and cataract surgery.

Methods: The Blue Mountains Eye Study examined 3654 participants > or = 49 years of age during 1992-4, then 2335 survivors (75.1%) after five years.

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Parents of 134 children (age 5-18 years; 84% participation) attending a private school gave informed consent for their child's participation in a pilot study to demonstrate the feasibility and estimate sample size for a larger study of myopia prevalence, the Sydney Myopia Study. LogMAR visual acuity and other ocular assessments, including cycloplegic autorefraction (tropicamide 1%) and examination of the media and fundus, were performed. The prevalence of significant ocular conditions was 28.

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Purpose: To assess whether an association exists between myopia and incident cataract and cataract surgery in an older population-based cohort study.

Methods: The Blue Mountains Eye Study examined 3654 participants aged 49 years or more during 1992 to 1994 and then 2334 (75.1%) of the survivors after 5 years.

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Purpose: To assess whether an association exists between iris color and the incidence of cataract and cataract surgery.

Design: Population-based cohort study.

Methods: The Blue Mountains Eye Study examined 3654 predominantly Caucasian participants aged 49+ years during 1992-1994, and then 2335 survivors (75.

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The authors aimed to assess the relation between endogenous and exogenous female hormones and the incidence of age-related cataract and cataract surgery. The Blue Mountains Eye Study examined 2,072 women aged 49 years or older during 1992-1994, of whom 1,343 (74.0% of survivors) were reexamined after 5 years, during 1997-1999.

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The aim of this study was to assess whether socioeconomic status influenced the incidence of cataract surgery in a defined population of older Australians. The Blue Mountains Eye Study examined 3654 residents during 1992-1994, then 2334 survivors (75.1%)during 1997-1999.

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