A randomized, controlled trial of corneal collagen cross-linking in progressive keratoconus: three-year results.

Purpose: To report the refractive, topographic, and clinical outcomes 3 years after corneal collagen cross-linking (CXL) in eyes with progressive keratoconus.

Design: Prospective, randomized controlled trial.

Participants: One hundred eyes with progressive keratoconus were randomized into the CXL treatment or control groups.

Localized changes in stromal reflectivity after corneal collagen cross-linking observed with different imaging techniques.

Purpose: To report changes observed in the corneal stroma using confocal microscopy and Scheimpflug imaging following epithelium-off collagen cross-linking (CXL) in cases of progressive keratoconus.

Methods: Fifteen eyes of 14 patients were examined before and after CXL using slit-lamp biomicroscopy, Scheimpflug imaging, and confocal microscopy. A subset of patients also had optical coherence tomography imaging performed.

A randomized controlled trial of corneal collagen cross-linking in progressive keratoconus: preliminary results.

Purpose: This prospective, randomized, controlled trial aims to provide evidence in relation to the efficacy and safety of corneal collagen cross-linking (CXL) in the management of progressive keratoconus.

Methods: Eligible eyes were separately randomized into either treatment or control groups. Collagen crosslinking was performed using 0.