Financial implications of obesity.

The obesity epidemic continues to grow. As the number of obese people increases, it is logical to expect an increasing number of obese patients and increasing costs to care for these patients. Orthopedic surgeons will see many of these patients who need treatment for injuries and chronic conditions.

The time course of transcriptional regulation in anoxic fibroblasts: implications for carpal tunnel syndrome - biomed 2010.

Unlabelled: Hypoxia is the initial cellular insult in carpal tunnel syndrome. While much is known about the gross and histological progression of this prevalent disease, little is currently known about its molecular basis. Additionally, some debate presently exists regarding whether the disease occurs as the result of an inflammatory or a fibrotic pathology.

Connective tissue growth factor (ctgf) expression in the tenosynovium of patients with carpal tunnel syndrome - biomed 2009.

Connective Tissue Growth Factor (CTGF) expression has been identified in a wide variety of fibrotic disorders; however, the expression of CTGF in carpal tunnel syndrome (CTS) has not yet been described in the literature. Both inflammatory and fibrotic etiologies have been implicated in the pathogenesis of CTS, with current evidence favoring an emphasis on a non-inflammatory fibrosis pathophysiological picture. Our objective was to identify whether CTGF is expressed in the tenosynovium of patients with CTS.