Publications by authors named "Christine Van Winssen"
Article Synopsis
- Epilepsy care in Ontario faces significant challenges including limited bed availability in Epilepsy Monitoring Units (EMU), restricted surgical options, and inadequate community support, especially following the COVID-19 pandemic.* -
- A 44-item survey was conducted across all 11 adult and pediatric epilepsy centers in Ontario, collecting both quantitative and qualitative data on the current state of epilepsy care.* -
- Findings showed persistent gaps in care due to EMU bed pressures and workforce shortages, prompting the formation of a clinical network to help improve access to epilepsy services in the region.*
Objectives: To examine the psychometric characteristics of the Nepean Belief Scale (NBS) in psychiatric inpatients with delusions. The NBS is a five-item, clinician-administered scale that assesses the characteristics of beliefs, i.e.
View Article and Find Full Text PDFWhich behavioral test is the most sensitive for detecting cognitive deficits in the 3xTg-AD at 6.5 months of age? The 3xTg-AD mouse model of Alzheimer's disease (AD) has three transgenes (APPswe, PS1M146V, and Tau P301L) which cause the development of amyloid beta plaques, neurofibrillary tangles, and cognitive deficits with age. In order to determine which task is the most sensitive in the early detection of cognitive deficits, we compared male and female 3xTg-AD and B6129SF2 wildtype mice at 6.
View Article and Find Full Text PDFThe 3xTg-AD mouse has high validity as a model of Alzheimer's disease (AD) because it develops both amyloid beta plaques and neurofibrillary tangles. Human patients with AD typically develop motor deficits, which worsen as the disease progresses, but 3xTg-AD mice have been reported to show enhanced motor abilities. We investigated the motor behaviour phenotype of male and female 3xTg-AD and B6129SF2 wildtype mice on a battery of motor behaviours at 6 months of age.
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