Publications by authors named "Christine Stebler"

Introduction: INTERCEPT treatment is used to reduce platelet transfusion associated bacterial infections. Limited data are available in Switzerland.

Patients And Methods: Patients with thrombocytopenia or thrombocyte dysfunction requiring platelet transfusions were enrolled in a prospective cohort study on safety (primary endpoint) and efficacy (secondary endpoint) of INTERCEPT treated platelets (I-PLTs).

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Background: Iron store deficiency is a common side effect of whole blood donation. Early recognition and reversal of excessive iron loss may avoid symptomatic iron store depletion in blood donors and reduce volunteer loss due to iron deficiency (ID) anemia.

Study Design And Methods: Between 1996 and 2009, a total of 160,612 visits with the intention to donate blood by 23,557 healthy volunteers were recorded at our center.

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Article Synopsis
  • - The study investigates the prevalence and behavior of BK virus (BKV) and JC virus (JCV) in 400 healthy blood donors, revealing that 82% are seropositive for BKV and 58% for JCV, with variation in prevalence as age increases.
  • - Asymptomatic urinary shedding of the viruses occurs in 7% of subjects for BKV and 19% for JCV, showing different correlations between urinary viral loads and IgG levels for each virus.
  • - The findings highlight significant differences in how BKV and JCV interact with the immune system in healthy individuals, underscoring unique patterns in their infection and replication behavior.
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The anterior nares are the most important screening site of colonization with Staphylococcus aureus. We screened 2966 individuals for S. aureus carriage with swabs of both nares and throat.

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