Publications by authors named "Christine Ruehle"
Pharmacokinetics and Safety of Ceftobiprole in Pediatric Patients.
Pediatr Infect Dis J
November 2021
Article Synopsis
- Ceftobiprole is a broad-spectrum cephalosporin antibiotic approved for treating pneumonia in adults, and recent studies have explored its use in pediatric populations.
- Two studies examined its pharmacokinetics and safety in neonates and children up to 17 years, with similar plasma concentration and exposure results compared to adults.
- The drug was well tolerated, maintaining effective concentrations for a significant period and demonstrating potential effectiveness in achieving pharmacokinetic-pharmacodynamic goals in pediatric patients.