Publications by authors named "Christine R Lopez"
Article Synopsis
- The study investigates the link between long-term blood glucose levels (measured by hemoglobin A1c, HbA1c) and the development of Acute Respiratory Distress Syndrome (ARDS) among critically ill adults who are at risk for ARDS.
- It analyzes data from two cohorts, finding that patients with diabetes did not have a significantly higher risk of ARDS compared to nondiabetics; however, those with poorly controlled diabetes (high HbA1c) had an increased risk.
- While the findings were not consistent across both cohorts, the combined analysis suggests that high HbA1c levels could indicate an elevated risk for ARDS, particularly in patients with diabetes.
Purpose: A case of loperamide-induced recurrent torsades de pointes is reported to raise awareness of an increasingly common phenomenon that could be encountered by medical providers during the current opioid epidemic.
Summary: A 40 year-old-man with a prior history of opioid abuse who presented to the emergency department after taking up to 100 tablets of loperamide 2 mg daily for 5 years to blunt opioid withdrawal symptoms and was subsequently admitted to the intensive care unit for altered mental status and hyperthermia. The patient had prolonged QTc and 2 episodes of torsades de pointes (TdP) that resulted in cardiac arrest with return of spontaneous circulation.