Commentary.

Due to the ongoing nature of the COVID-19 pandemic, I have decided to print the following commentary to help provide another alternative for reducing potential exposure to and incidental transmission of SARS-CoV-2 during the provision of anesthesia for dentistry. -Kyle J. Kramer, Editor-in-Chief.

Serum mepivacaine concentrations after intraoral injection in young children.

The authors measured plasma concentrations of mepivacaine in 36 children from the ages of 2 to 5 years who received dental care under light general anesthesia. The subjects were randomly assigned to receive either 2 percent mepivacaine hydrochloride with 1:20,000 levonordefrin or 3 percent mepivacaine hydrochloride without vasoconstrictor. The volume of anesthetic injected depended on the planned procedures for each patient.