Silver Sulfadiazine and Cerium Nitrate in Ischemic Skin Necrosis of the Leg and Foot: Results of a Prospective Randomized Controlled Study.

Flammacerium is a topical treatment composed of silver sulfadiazine and cerium nitrate initially used in burns. The objective was to assess the effectiveness of silver sulfadiazine and cerium nitrate on ischemic necrosis wounds of the lower limb as an alternative to amputation for a period of 12 weeks. Patients were prospectively randomized to receive silver sulfadiazine and cerium nitrate or standard care.

[Debridement dressings].

For any wound, necrosis is an obstacle to the formation of granulation tissue and creates an environment which is particularly favourable to the proliferation of bacteria. Mechanical debridement, carried out by a doctor or nurse, or surgical debridement, is usually necessary. It is completed by autolytic debridement using technical dressings.

Clinical impact of negative-pressure wound therapy: a 1,126-patient observational prospective study.

Negative-pressure wound therapy (NPWT) was developed in the early 1990s and reported in 1997 by Argenta and Morykwas. Ignored at first, this technique progressively came to be considered as an outstanding advancement in reconstructive surgery. Several randomized controlled studies produced evidence for the effect of NPWT on promotion of granulation tissue formation and prevention of tissue damage and amputation.

[Negative pressure treatment devices].

Negative pressure therapy systems comprise several types of devices and dressings. Some are specific to particular clinical situations.

[Compression material].

The compression of a venous ulcer is carried out with the use of bandages, and for less exudative ulcers, with socks, stockings or tights. The system of bandages is complex. Different forms of extension and therefore different types of models exist.

Efficacy and safety of Hylan G-F 20 in shoulder osteoarthritis with an intact rotator cuff. Open-label prospective multicenter study.

Objective: To evaluate the feasibility, safety, and symptomatic efficacy of intra-articular Hylan G-F 20 in patients with shoulder osteoarthritis and an intact rotator cuff.

Methods: Open-label, prospective, multicenter study in patients with pain scores on a visual analog scale (VAS) between 40/100 and 90/100. An intra-articular injection of 2 ml of Hylan G-F 20 was given under fluoroscopic guidance.