Best disease presenting as a giant serous pigment epithelial detachment.

Purpose: To report a case of Best disease presenting as a giant serous pigment epithelial detachment and misdiagnosed as central serous chorioretinopathy.

Methods: Clinical examination and multimodal imaging, including color fundus photography, fluorescein angiography, fundus autofluorescence, and spectral domain optical coherence tomography are presented, as well as the results of electrooculography.

Results: A 54-year-old Asian man underwent photodynamic therapy for a large serous pigment epithelial detachment presumed to be due to central serous chorioretinopathy.

Melanocytoma of the optic disc associated with visual field defects: clinical features and imaging characteristics.

The authors studied the clinical features, visual field, and spectral-domain optical coherence tomography (SD-OCT) characteristics of peripapillary melanocytoma associated with visual field defects in two eyes of two patients. Both eyes had hyperreflective anterior surface and posterior optical shadowing in the region of peripapillary melanocytoma on SD-OCT imaging. The retinal nerve fiber layer was thin adjacent to these lesions, and this corresponded to the opposite hemifield defect on Humphrey Visual Field testing.

Epithelioid angiosarcoma: a neoplasm with potential diagnostic challenges.

Epithelioid angiosarcomas are extremely rare tumors associated with poor prognosis and early metastases. Its epithelioid cytomorphology and limited vasoformation make it difficult to distinguish from more common malignancies, such as, carcinoma. This can be a potential diagnostic pitfall for the cytopathologist.