Publications by authors named "Christine Ernst"
Transfusion-dependent thalassaemia (TDT) requires red blood cell concentrates (RBCC) to prevent complications of anaemia, but carries risk of infection. Pathogen reduction of RBCC offers potential to reduce infectious risk. We evaluated the efficacy and safety of pathogen-reduced (PR) Amustaline-Glutathione (A-GSH) RBCC for TDT.
View Article and Find Full Text PDFArticle Synopsis
- The study evaluated the effectiveness of amustaline-treated red blood cells (RBCs) compared to conventional RBCs to enhance the safety of transfusions and prevent disease transmission during cardiac surgery.
- Results showed that while amustaline-treated RBCs had a slightly lower mean hemoglobin content, they still met safety guidelines and did not lead to significant differences in clinical outcomes or adverse events.
- The findings suggest that amustaline-treated RBCs are a viable option for transfusions, with no immune response detected and potential benefits for future studies on cardiac surgery.
The purpose of this study was the analysis of psychological distress and health-related quality of life (HRQoL) of parents with minor children during curative resp. palliative treatment.Cross-sectional design with a sample of N=89 parent dyads.
View Article and Find Full Text PDFDepression is a common and often harmful disorder, which is frequently associated with the winter season. Research has shown a link between type 2 diabetes mellitus and depression. Furthermore, diabetics with depression have a higher rate of adverse outcomes.
View Article and Find Full Text PDFObjective: OSHA criteria for recording occupational noise-induced hearing loss (NIHL) do not ensure early detection, yet scientific consensus is lacking regarding optimal "early flags" for NIHL. This study compares early flag metrics to the subsequent development of recordable hearing loss.
Methods: In a longitudinal analysis of industrial audiograms, we calculated time from flag event to recordable hearing loss as well as 10 year risk of recordable hearing loss following flag occurrence.