Publications by authors named "Christine Erevik"

Article Synopsis
  • This study investigated the effects of high-intensity endurance exercise on cardiac troponin I (cTnI) levels in healthy individuals, distinguishing between high and normal cTnI responders.
  • Participants, including mountain bike race participants, underwent rigorous exercise tests and echocardiography to assess changes in heart function.
  • Although high cTnI responders showed lower regional strain in certain heart muscle segments immediately after exercise, there were no lasting impacts on overall heart function, suggesting that these changes are not harmful in the long term.
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The relationship between exercise-induced troponin elevation and non-obstructive coronary artery disease (CAD) is unclear. This observational study assessed non-obstructive CAD's impact on exercise-induced cardiac Troponin I (cTnI) elevation in middle-aged recreational athletes. cTnI levels of 40 well-trained recreational athletes (73% males, 50 ± 9 years old) were assessed by a high-sensitive cTnI assay 24 h before, and at 3 and 24 h following two high-intensity exercises of different durations; a cardiopulmonary exercise test (CPET), and a 91-km mountain bike race.

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Article Synopsis
  • The study investigates how prolonged, high-intensity endurance exercise affects the heart's left ventricular (LV) function, specifically looking at myocardial work and fatigue using echocardiography.
  • It included 59 recreational athletes and compared their heart response after a cardiopulmonary exercise test (CPET) and a challenging 91-km mountain bike race, highlighting significant differences in exercise duration, heart rate, and cardiac stress markers (cTnI).
  • The findings reveal that while high-intensity exercise increased myocardial inefficiency (wasted work) and led to fatigue, there were no immediate changes in LV ejection fraction and global longitudinal strain, suggesting that heart efficiency markers may decline before noticeable drops in overall heart function.
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Background Postexercise cardiac troponin levels show considerable interindividual variations. This study aimed to identify the major determinants of this postexercise variation in cardiac troponin I (cTnI) following 3 episodes of prolonged high-intensity endurance exercise. Methods and Results Study subjects were recruited among prior participants in a study of recreational cyclists completing a 91-km mountain bike race in either 2013 or 2014 (first race).

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Background: Dietary supplement use among recreational athletes is common, with the intention of reducing inflammation and improving recovery. We aimed to describe the relationship between omega-3 fatty acid supplement use and inflammation induced by strenuous exercise.

Methods: C-reactive protein (CRP) concentrations were measured in 1002 healthy recreational athletes before and 24 h after a 91-km bicycle race.

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Background: Recent cross-sectional studies have suggested a dose-dependent relationship between lifelong exposure to physical activity and the burden of calcified coronary artery disease (CAD). No longitudinal studies have addressed this concern.

Hypothesis: Exercise volume is associated with progression of coronary artery calcium (CAC), defined as ≥10 units increase in CAC score.

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