Publications by authors named "Christine Dew"
Article Synopsis
- Genome-wide association studies in reproductive medicine are identifying key genetic variants linked to diseases, but relevant tissue samples, particularly the endometrium, are often overlooked in molecular profiling approaches.
- Researchers examined variability in DNA methylation and RNA expression in endometrial tissue, endometriosis samples, and abdominal fat from women, finding that individual differences were more significant than variations caused by tissue type or technical issues.
- The study revealed menstrual phase and age significantly impacted methylation patterns in endometrium and endometriotic tissues, while distinct methylation signatures between endometrial and endometriotic tissues pointed to pathways involved in signaling and hormone regulation.
