Predictive Radiation Oncology - A New NCI-DOE Scientific Space and Community.

With a widely attended virtual kickoff event on January 29, 2021, the National Cancer Institute (NCI) and the Department of Energy (DOE) launched a series of 4 interactive, interdisciplinary workshops-and a final concluding "World Café" on March 29, 2021-focused on advancing computational approaches for predictive oncology in the clinical and research domains of radiation oncology. These events reflect 3,870 human hours of virtual engagement with representation from 8 DOE national laboratories and the Frederick National Laboratory for Cancer Research (FNL), 4 research institutes, 5 cancer centers, 17 medical schools and teaching hospitals, 5 companies, 5 federal agencies, 3 research centers, and 27 universities. Here we summarize the workshops by first describing the background for the workshops.

Terahertz optical thickness and birefringence measurement for thermal barrier coating defect location.

We present a normal incidence terahertz reflectivity technique to determine the optical thickness and birefringence of yttria-stabilized zirconia (YSZ) thermal barrier coatings (TBCs). Initial verification of the method was achieved by measurement of a set of fused silica calibration samples with known thicknesses and showed excellent agreement (<1% of refractive index) with the literature. The THz-measured optical thickness and its variation through the depth profile of the YSZ coating are shown to be in good agreement (<4%) with scanning electron microscope cross-sectional thickness measurements.

Thermal Insulation of YSZ and Erbia-Doped Yttria-Stabilised Zirconia EB-PVD Thermal Barrier Coating Systems after CMAS Attack.

The impact of small deposits of calcium-magnesium-aluminium silicates (CMAS) on the top of thermal barrier coatings (TBCs) made of yttria-stabilised zirconia (YSZ) produced via electron-beam physical vapour deposition (EB-PVD) is shown to play a role in the microstructural and chemical stability of the coatings; hence, it also affects the thermal insulation potential of TBCs. Therefore, the present work investigates the degradation potential of minor CMAS deposits (from 0.25 to 5 mg·cm) annealed at 1250 °C for 1 h on a novel ErO-YO co-stabilised ZrO (ErYSZ) EB-PVD TBC, which is compared to the standard YSZ coating.