Publications by authors named "Christine Bo Hansen"
SARS-CoV-2 Antibodies in Breastmilk Three and Six Months Postpartum in Relation to the Trimester of Maternal SARS-CoV-2 Infection-An Exploratory Study.
Int J Mol Sci
March 2024
Article Synopsis
- The study investigates the presence and duration of SARS-CoV-2 antibodies (IgA and IgG) in the breastmilk and blood serum of mothers infected during pregnancy, focusing on data collected three and six months after childbirth.
- Results show variation in antibody frequency and concentration, with the highest breastmilk IgA found six months postpartum in mothers infected during the third trimester, and detectable serum IgA lasting over 400 days post-infection.
- No correlation was found between serum and breastmilk IgA or IgG, highlighting complexities in how maternal antibodies are transferred and maintained in breastmilk.
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may affect the male reproductive system as it uses angiotensin-converting enzyme (ACE)2, which is expressed in testicular tissue, as an entry point into the cell. Few studies have evaluated the long-term effects of mild coronavirus disease 2019 (COVID-19) on testicular function, and insulin-like factor 3 (INSL3) levels have not previously been assessed during acute SARS-CoV-2 infection.
Objectives: The aim of the study was to assess the impact of acute SARS-CoV-2 infection on testicular function including INSL3 and the presence of SARS-CoV-2 RNA in semen in non-hospitalised men with mild COVID-19.
This article reviews the current studies published on the transmission of SARS-CoV-2 in semen and the potential effect of COVID-19 on male fertility. The aim was to provide insight into different possible mechanisms of involvement of the male reproductive system by SARS-CoV-2 infection and to evaluate the studies investigating the presence of virus in semen. It is concluded that the likelihood of SARS-CoV-2 transmission through semen is low and that COVID-19 may negatively affect semen parameters, but that the impairment is probably short-termed.
View Article and Find Full Text PDF