Publications by authors named "Christine Basmadjian"
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Synopsis of recent research by authors named "Christine Basmadjian"
Christine Basmadjian's research focuses on the development of inhibitors targeting specific kinases and their implications in cancer therapeutics, particularly enhancing selectivity and potency against key enzyme pathways such as NF-κB and Nek7.
She has explored the therapeutic potential of flavaglines, natural compounds with cytoprotective and anti-inflammatory properties, demonstrating their effectiveness in protecting against doxorubicin-induced cardiotoxicity and improving intestinal health during inflammation.
Basmadjian's work also highlights the intricate mechanisms of resistance to cancer therapies, particularly involving the eIF4F complex, underscoring the importance of understanding molecular pathways to innovate more effective treatment strategies.