An allometric model to estimate fluid requirements in children following burn injury.

Objectives: To evaluate the ability of an allometric 3/4 Power Model combined with the Galveston Formula (Galveston-3/4 PM Formula) to predict fluid resuscitation requirements in children suffering burn injuries in comparison with the frequently used Parkland Formula and Galveston Formula using the Du Bois formula for surface area estimation (Galveston-DB Formula).

Aim: To demonstrate that the Galveston-3/4 PM Formula is clinically equivalent to the Galveston-DB Formula for the estimation of fluid requirements in pediatric burn injury cases.

Background: Fluid resuscitation requirements differ in children suffering burn injuries when compared to adults.

Fraser Health PACS project: learning from experience in planning.

Fraser Health is proud of its new imaging technology. Making the transition from film to PACS has proven to be both rewarding and challenging. PACS is now performing as planned, providing physicians and health care providers with a faster, safer, more streamlined imaging service than ever before.

Spontaneous ventilation with remifentanil in children.

Background: Remifentanil is a short-acting drug that allows us to study the specific respiratory effects of potent opioid analgesics. The purpose of this study is to describe the effects of a remifentanil infusion during spontaneous ventilation in children. Pharmacokinetic studies provide useful information on the time course of opioid blood concentrations; however, they cannot be easily translated into infusion administration guidelines for pediatric clinical practice.

Increased tidal volume variability in children is a better marker of opioid-induced respiratory depression than decreased respiratory rate.

Objective: During opioid administration, decreasing respiratory rate is typically used as a predictor of respiratory depression. Prior to opioid-induced apnea, progressively irregular breathing patterns have been noticed. We hypothesize that opioid administration to children will increase tidal volume variability (TV(var)) and that this will be a better predictor of respiratory depression than a decrease in respiratory rate.