Publications by authors named "Christina-Panagiota Koutsouri"

Bloodstream infections (BSIs) can be primary or secondary, with significant associated morbidity and mortality. Primary bloodstream infections (BSIs) are defined as infections where no clear infection source is identified, while secondary BSIs originate from a localized infection site. This study aims to compare patterns, outcomes, and medical costs between primary and secondary BSIs and identify associated factors.

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Introduction: Infections impose a significant burden on healthcare costs worldwide. We aimed to explore antibiotic- and hospital-related costs of infections needing admission in a tertiary university hospital in Greece.

Methods: We performed a prospective cohort study in the medical care unit of a tertiary university hospital in Greece, for the period May 2016 to May 2018.

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Article Synopsis
  • Prompt empiric antibiotic therapy (EAT) is crucial for treating infections, but many blood cultures don’t identify the pathogens, prompting a study on EAT patterns, outcomes, and costs in a university hospital.
  • An analysis of 489 patients showed that intra-abdominal infections were most common, with a 67% success rate for EAT, while factors like urinary tract infections reduced failure chances, and sepsis increased them significantly.
  • Patients with EAT failure faced longer hospital stays, higher antibiotic usage, and increased hospitalization costs, emphasizing the financial impact of unsuccessful treatments.
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