Publications by authors named "Christina Schlegl"
Article Synopsis
- Research shows that despite current prevention methods, early recurrent strokes are still common, especially in patients with atherosclerosis, with over 10% experiencing repeat events.
- A new mouse model revealed that strokes activate the AIM2 inflammasome in atherosclerotic plaques due to increased circulating cell-free DNA, leading to inflammation, plaque destabilization, and recurrent strokes.
- Targeting the mechanisms of DNA-mediated inflammasome activation may offer new treatment options to reduce the high rate of recurrent strokes in at-risk patients.