Publications by authors named "Christina Muhs"
Article Synopsis
- Metabolism significantly influences cancer progression, with a focus on glucose as a key energy source, while the role of other natural sugars is less understood.
- This study used advanced 2D NMR spectroscopy to analyze the metabolism of C-labelled sugars (glucose, fructose, galactose, mannose, and xylose), revealing that mannose mimics glucose’s metabolic profile, and galactose plays a crucial role in one-carbon metabolism alongside fructose.
- The findings indicate that cancer cells utilizing fructose or galactose show reduced sensitivity to certain inhibitors, suggesting these sugars are essential in understanding metabolism in cancer treatments.
The current pandemic situation caused by the Betacoronavirus SARS-CoV-2 (SCoV2) highlights the need for coordinated research to combat COVID-19. A particularly important aspect is the development of medication. In addition to viral proteins, structured RNA elements represent a potent alternative as drug targets.
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