Mobile App Interventions for Parkinson's Disease, Multiple Sclerosis and Stroke: A Systematic Literature Review.

Central nervous system diseases (CNSDs) lead to significant disability worldwide. Mobile app interventions have recently shown the potential to facilitate monitoring and medical management of patients with CNSDs. In this direction, the characteristics of the mobile apps used in research studies and their level of clinical effectiveness need to be explored in order to advance the multidisciplinary research required in the field of mobile app interventions for CNSDs.

The Anti-tuberculosis Battle in Greece in the 1800s and 1900s.

Tuberculosis is an infectious disease that mainly affects the lungs (known as pulmonary tuberculosis). is a species of pathogenic bacteria in the family of Mycobacteriaceae and the causative agent of tuberculosis; it was discovered by Robert Koch in 1882. From about 1918 to 1939, tuberculosis in Greece was characterized as a social disease because it seemed to spread among the lower social classes, including displaced people living in refugee camps.

Differences Between Exergaming Rehabilitation and Conventional Physiotherapy on Quality of Life in Parkinson's Disease: A Systematic Review and Meta-Analysis.

Parkinson's disease (PD) is a neurodegenerative condition with both motor and non-motor symptoms affecting the quality of life (QoL) of older adults. Exergaming rehabilitation allows the interaction of the subject with digital games through the implementation of repetitive functional activities. Conventional physiotherapy uses patient-centered programs that include a variety of active exercises.

RESPOnSE-A Framework for Enforcing Risk-Aware Security Policies in Constrained Dynamic Environments.

The enforcement of fine-grained access control policies in constrained dynamic networks can become a challenging task. The inherit constraints present in those networks, which result from the limitations of the edge devices in terms of power, computational capacity and storage, require an effective and efficient access control mechanism to be in place to provide suitable monitoring and control of actions and regulate the access over the resources. In this article, we present RESPOnSE, a framework for the specification and enforcement of security policies within such environments, where the computational burden is transferred to high-tier nodes, while low-tier nodes apply risk-aware policy enforcement.

Reliability, validity and minimal detectable change of the Mini-BESTest in Greek participants with chronic stroke.

Objectives: This study aimed to investigate the psychometric characteristics of reliability, validity and ability to detect change of a newly developed balance assessment tool, the Mini-BESTest, in Greek patients with stroke.

Design: A prospective, observational design study with test-retest measures was conducted.

Methods: A convenience sample of 21 Greek patients with chronic stroke (14 male, 7 female; age of 63 ± 16 years) was recruited.

Translation into Greek and initial validity and reliability testing of a modified version of the SCIM III, in both English and Greek, for self-use.

Purpose: To translate and culturally adapt the Spinal Cord Injury Measure version III (SCIM III) into Greek (GR-SCIM III). To conduct initial testing of psychometric properties of both measures by self-report.

Method: Forward-backward translation was conducted to produce the GR-SCIM III.

A systematic review of the prevalence of musculoskeletal pain, back and low back pain in people with spinal cord injury.

Purpose: To review and summarise the prevalence of chronic back pain (CBP), chronic low back pain (CLBP) and chronic musculoskeletal pain (CMSKP) in people with spinal cord injury (SCI) and evaluate how pain is assessed.

Method: A systematic literature review between 1990 and 2012 in English language journals. Twelve databases were searched including CINAHL, Cochrane, Embase, PubMed and Science direct.

Dissecting the roles of Raf- and PI3K-signalling pathways in melanoma formation and progression in a zebrafish model.

Deregulated Ras signalling is implicated in most human neoplasia, exemplified by melanoma. Whereas Raf activation occurs almost ubiquitously in benign and malignant melanocytic neoplasms, implying an involvement in tumour initiation, phosphoinositide 3-kinase (PI3K) activation occurs predominantly in malignant neoplasms, implying an involvement in malignant progression. Here, we dissect the contributions of these two pathways to tumourigenesis in vivo, by modulating their activities in zebrafish melanocytes.