Central neurocytoma: management recommendations based on a 35-year experience.

Purpose: To examine the outcomes of patients with histologically confirmed central neurocytomas.

Methods And Materials: The data from 45 patients with central neurocytomas diagnosed between 1971 and 2003 were retrospectively evaluated. Various combinations of surgery, radiotherapy (RT), and chemotherapy had been used for treatment.

A methodology to determine margins by EPID measurements of patient setup variation and motion as applied to immobilization devices.

Assessment of clinic and site specific margins are essential for the effective use of three-dimensional and intensity modulated radiation therapy. An electronic portal imaging device (EPID) based methodology is introduced which allows individual and population based CTV-to-PTV margins to be determined and compared with traditional margins prescribed during treatment. This method was applied to a patient cohort receiving external beam head and neck radiotherapy under an IRB approved protocol.