Publications by authors named "Christina Kottooran"

Article Synopsis
  • The study aimed to understand how different pressures in the renal pelvis during ureteroscopy affect the likelihood of infection using a pig model.
  • Researchers performed ureteroscopy on pigs while controlling the renal pelvis pressure at either 37 mmHg or 75 mmHg and infused saline with or without E. coli to track infection rates and inflammatory responses.
  • Results showed that higher pressure (75 mmHg) combined with E. coli irrigation led to significant increases in inflammatory markers and bacteraemia, compared to lower pressure and saline alone.
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Introduction: Patients presenting with an obstructing ureteral stone and urinary tract infection (UTI) are at risk for severe infectious complications. Historically, diabetes mellitus (DM) was considered a risk factor for the development of septic shock in these patients. This study aimed to evaluate DM's impact on risk of septic shock in ureteral stent placement for ureteral stone and presumed UTI.

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Systemic inflammatory response syndrome (SIRS) criteria have long been used to predict septic shock. The sequential organ failure assessment and quick sequential organ failure assessment (qSOFA) scores have been suggested to be more accurate predictors. This study aims to compare SIRS and qSOFA for predicting of septic shock in the setting of retrograde ureteral stenting for obstructing stones and concomitant urinary tract infection.

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Objective: To evaluate the relationship between renal pelvis pressure and fluid absorption during ureteroscopy (URS) in a live porcine model.

Materials And Methods: Flexible URS (fURS) was performed in anaesthetised female Yorkshire pigs. Prior to performing fURS, a 0.

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In recent years, the use of opioids in medical practice has come under significant scrutiny. This, in part, is owing to evidence of overprescription and overuse of opioid medications, as well as the unintended consequences and side effects for patients who take these medications. Here, we review the role of opioids and the responsible use of these medications with respect to kidney stone disease and surgical interventions for kidney stones.

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