Publications by authors named "Christina Kanonidou"
Article Synopsis
- Latent fibrin clots can lead to inaccurate immunoassay results, impacting thyroid function tests (TFTs), especially in patients with congenital dysfibrinogenemia (CD).
- A case study highlights that plasma samples from a patient with Graves' disease and CD provided more accurate TFT results than serum samples, which were unreliable.
- This report emphasizes the need to recognize CD as a potential cause of discordant TFT results to avoid unnecessary medical interventions and to help identify undiagnosed cases.
Article Synopsis
- Ehlers-Danlos syndromes (EDS) are genetic disorders that affect connective tissue, and there are 13 different types of EDS.
- Researchers studied 174 EDS patients who didn't have a clear genetic diagnosis to find out more about their conditions using advanced genetic testing called whole exome sequencing (WES).
- They discovered several genetic variants related to EDS and other similar disorders, showing that more research and better testing can help identify difficult cases and improve diagnosis.
Background: The causal relationship between low-density lipoprotein (LDL) and atherosclerotic cardiovascular disease (CVD) has been firmly substantiated. LDL consists of a heterogeneous group of particles with different physicochemical and metabolic properties. Among them, small dense LDL (sdLDL) particles are considered an emerging CVD risk factor and a promising CVD risk biomarker.
View Article and Find Full Text PDFPurpose: Ehlers-Danlos syndrome (EDS) comprises a group of overlapping hereditary disorders of connective tissue with significant morbidity and mortality, including major vascular complications. We sought to identify the diagnostic utility of a next-generation sequencing (NGS) panel in a mixed EDS cohort.
Methods: We developed and applied PCR-based NGS assays for targeted, unbiased sequencing of 12 collagen and aortopathy genes to a cohort of 177 unrelated EDS patients.
Purpose: To evaluate the impact of contact lenses wear vs. spectacles wear on visual function of young adults with mild to moderate myopia.
Methods: 57 students (27 male and 30 female) with a mean age of 23 years old participated in the study.
Introduction. We report a case of unilateral optic disc edema in a paediatric patient and discuss the concerns involved in diagnosis and management of similar cases. Materials and Methods.
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