Diagnostic accuracy of elastography and magnetic resonance imaging in patients with NAFLD: A systematic review and meta-analysis.

Background And Aims: Vibration-controlled transient elastography (VCTE), point shear wave elastography (pSWE), 2-dimensional shear wave elastography (2DSWE), magnetic resonance elastography (MRE), and magnetic resonance imaging (MRI) have been proposed as non-invasive tests for patients with non-alcoholic fatty liver disease (NAFLD). This study evaluated their diagnostic accuracy for liver fibrosis and non-alcoholic steatohepatitis (NASH).

Methods: PubMED/MEDLINE, EMBASE and the Cochrane Library were searched for studies examining the diagnostic accuracy of these index tests, against histology as the reference standard, in adult patients with NAFLD.

Mapping tissue water T in the liver using the MOLLI T method in the presence of fat, iron and B inhomogeneity.

Modified Look-Locker inversion recovery (MOLLI) T mapping sequences can be useful in cardiac and liver tissue characterization, but determining underlying water T is confounded by iron, fat and frequency offsets. This article proposes an algorithm that provides an independent water MOLLI T (referred to as on-resonance water T ) that would have been measured if a subject had no fat and normal iron, and imaging had been done on resonance. Fifteen NiCl -doped agar phantoms with different peanut oil concentrations and 30 adults with various liver diseases, nineteen (63.