Publications by authors named "Christina Hillbricht"
Article Synopsis
- This study investigates the impact of presurgical tumor growth and other clinical factors on the survival of glioblastoma (GBM) patients.
- A retrospective analysis of 98 adult GBM patients revealed that tumor growth rates did not significantly affect overall survival (OS) or progression-free survival (PFS).
- Key predictors of treatment outcomes included MGMT status, radiation dose, and the number of adjuvant cycles of temozolomide (TMZ), which can help inform personalized treatment plans.
Background/aim: To investigate the significance of the timing of chemoradiotherapy together with clinical and laboratory features in newly diagnosed glioblastoma.
Patients And Methods: Clinical and laboratory parameters of 209 patients with glioblastoma potentially influencing overall (OS) and progression-free (PFS) survival were analyzed in univariable and multivariable models.
Results: On univariable analyses, Karnofsky performance status (p<0.