Publications by authors named "Christina Gregor"

Background: Medical marijuana (MMJ) is available in Pennsylvania, and participation in the state-regulated program requires patient registration and receiving certification by an approved physician. Currently, no integration of MMJ certification data with health records exists in Pennsylvania that would allow clinicians to rapidly identify patients using MMJ, as exists with other scheduled drugs. This absence of a formal data sharing structure necessitates tools aiding in consistent documentation practices to enable comprehensive patient care.

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Background: Patient portal secure messaging allows patients to describe health-related behaviors in ways that may not be sufficiently captured in standard electronic health record (EHR) documentation, but little is known about how cannabis is discussed on this platform.

Objective: This study aimed to identify patient and provider secure messages that discussed cannabis and contextualize these discussions over periods before and after its legalization for medical purposes in Pennsylvania.

Methods: We examined 382,982 secure messages sent by 15,340 patients and 6101 providers from an integrated health delivery system in Pennsylvania, United States, from January 2012 to June 2022.

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Article Synopsis
  • Medical Marijuana (MMJ) is legal in Pennsylvania, but there's no integration of MMJ certification data into health records, making it challenging for healthcare providers to identify MMJ users among their patients.
  • To address this, a project developed a systematic protocol for chart reviews to extract consistent MMJ-related information from patient records at Geisinger.
  • The protocol proved effective, yielding high reliability in data extraction, and enabling better understanding and documentation of MMJ use among patients.
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Objective: The ReLink project aims to reintegrate diagnosed-but-untreated hepatitis-C-positive patients into medical care and initiate a therapy.

Material/methods: A retrospective search within the practice management system of a single center in Germany identified among 1965 hepatitis-C-positive patients 100 untreated patients with available contact details and meeting all inclusion criteria. Patients were contacted by 2 contact rounds.

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Article Synopsis
  • The hematopoietic cellular therapy (HCT) pharmacist plays a vital role in the care team for patients undergoing transplantation, but integrating pharmacists into clinical settings is still a challenge.* -
  • A study evaluated the implementation of a full-time HCT pharmacist at a rural Pennsylvania center over two years, documenting 1,531 patient encounters and addressing 2,156 medication-related issues with substantial positive outcomes in patient care.* -
  • Patient satisfaction was high, with 76% of surveyed patients and caregivers reporting strong satisfaction, while pharmacy services expanded to support additional patient populations beyond just allogeneic transplants.*
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Background: Processes such as prior authorization (PA) for medications, implemented by health insurance companies to ensure that safe, appropriate, cost-effective, and evidence-based care is provided to all members, have created inefficiencies within healthcare systems. Thus, healthcare systems have implemented supplemental processes to reduce burden and ensure efficiency, timeliness, and appropriate care.

Objective: Evaluate implementation outcomes of two initiatives related to PA for medications: a common record that records all PA-related information that was integrated into the health record and an auto-routing of specialty prescriptions to a hospital-owned specialty pharmacy.

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Article Synopsis
  • A systematic review was conducted to analyze different implementation strategies aimed at improving the use of statins in patients with high cholesterol, utilizing data from various medical databases up to October 2018.
  • The review identified 258 unique strategies across 86 trials, but many lacked key details regarding their execution, such as timing and dosage.
  • The findings suggest that certain strategies significantly reduced LDL-C levels, improved statin prescribing rates, and enhanced adherence to statin therapy, indicating that utilizing more strategies may lead to better outcomes.
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Background: Familial hypercholesterolemia (FH) is an inherited lipid disorder that confers high risk for premature cardiovascular disease but remains undertreated. Causes are multifactorial and multilevel, ranging from underprescribing (at the clinician-level) to medication nonadherence (at the patient-level). We evaluated patient and clinician stakeholder barriers and facilitators for treatment of FH to explore possible solutions to the problem.

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Objective: To determine the amount of variation in numbers and types of medications requiring prior authorization (PA) by insurance plan and type.

Methods: Most health insurance companies require PA for medications to ensure safe and effective use and contain costs. We generated 4 lists of medications that required PA during 2017 for commercial, marketplace, Medicaid, and Medicare plans.

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Purpose: The barriers and solutions to the current prior-authorization (PA) process at an integrated health system were evaluated.

Methods: Focus groups were conducted with patients at an integrated health system who also had insurance from an affiliated health plan and at least 1 denial for a medication in the past year. Semistructured interviews were conducted with medical staff (physicians, office staff, and PA experts).

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Background: Familial hypercholesterolemia (FH) affects more than one million Americans, and most individuals have not been formally diagnosed with the condition. Individuals with FH have markedly elevated serum low-density lipoprotein cholesterol (LDL-C) levels from birth that substantially increase their risk for early-onset cardiovascular (CV) events. Guideline-recommended treatments exist to lower LDL-C and reduce the risk of CV events in individuals with FH and hypercholesterolemia.

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Background: Pharmacist-led collaborative interventions can support improved medication use and adherence during transitions of care (TOC). Community pharmacists are not always actively connected with other health-care team professionals, however, and their confidence in having necessary information may vary.

Objective: To assess community pharmacists' perceptions of information, care provided, and communication, before and after a postdischarge intervention designed to increase communication between inpatient and community pharmacists.

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Objectives: To determine the impact of pharmacist-provided continuous care and electronic communication on readmissions among a group of high-risk patients.

Design: Pragmatic interventional study with 5:1 matched control.

Setting And Participants: Patients discharged from any of 4 hospitals with chronic obstructive pulmonary disease, pneumonia, heart failure, acute myocardial infarction, or diabetes within Pennsylvania.

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