Treatment of autoimmune urticaria with low-dose cyclosporin A: A one-year follow-up.

Patients with autoimmune urticaria (AIU) and positive autologous serum skin test (ASST) represent a more serious type of chronic urticaria that does not respond to treatment with antihistamines, but responds completely to systemic corticosteroids. Because of the chronic course of the disease, there is a risk of side-effects. Cyclosporin A (CsA) is an alternative treatment for patients with AIU.

Cutaneous granulomas with predominantly CD8(+) lymphocytic infiltrate in a child with severe combined immunodeficiency.

Background: Combined immunodeficiency disorders comprise a heterogeneous group of diseases characterized by both humoral and cell-mediated immunodeficiency. Cutaneous granulomas manifestations in children with combined immunodeficiency are rare.

Objective: We report the case of a 6-year-old boy who presented with disseminated cutaneous granulomas and a history of multiple infections.

Transgrediens et progrediens palmoplantar keratoderma (Greither disease) and confluent and reticulated papillomatosis of Gougerot and Carteaud in the same patient: a coincidental finding?

A 13-year-old patient with typical findings of transgrediens et progrediens palmoplantar keratoderma that developed confluent and reticulated papillomatosis of Gougerot and Carteaud is presented. Although coexistence of the two disorders might be coincidental, the possibility of common pathogenetic pathways resulting in alterations of keratinization could be of investigational interest.