Publications by authors named "Christina Burrows"
Article Synopsis
- Deep brain stimulation (DBS) targeting the medial forebrain bundle shows promise as a treatment for therapy-resistant depression, with effects lasting up to 5 years in some patients.
- The study tracked 10 patients, assessing improvements using the Montgomery-Åsberg Depression Rating Scale, with significant reductions in scores post-stimulation.
- Key recommendations for future studies include extending the sham stimulation phase and integrating functional imaging to better understand treatment effects.
Deep brain stimulation (DBS) to the superolateral branch of the medial forebrain bundle (MFB) has been reported to lead to rapid antidepressant effects. In this longitudinal study, we expand upon the initial results we reported at 26 weeks (Fenoy et al., 2016), showing sustained antidepressant effects of MFB DBS on six patients with treatment-resistant depression (TRD) over 1 year.
View Article and Find Full Text PDFEbola virus disease (EVD), caused by Ebola virus (EBOV), is a severe illness characterized by case fatality rates of up to 90%. The sporadic nature of outbreaks in resource-limited areas has hindered the ability to characterize the pathogenesis of EVD at all stages of infection but particularly early host responses. Pathogenesis is often studied in nonhuman primate (NHP) models of disease that replicate major aspects of human EVD.
View Article and Find Full Text PDFArticle Synopsis
- Treatment resistant depression (TRD) is a challenging condition, and a new study on deep brain stimulation (DBS) targeting the medial forebrain bundle (MFB) has shown promise for rapid antidepressant effects in some patients.
- An interim analysis showed that three out of four patients experienced significant improvement in depression symptoms within one week of starting DBS, while one patient did not respond and withdrew from the study.
- Although the findings are preliminary and based on a small sample, they suggest that MFB-DBS may have similar effects to previously reported studies, highlighting the need for further research to confirm its effectiveness.
Objective: To evaluate the contribution of social communication abilities and affective/behavioral functioning to social integration outcomes for persons with traumatic brain injury (TBI).
Design: Prospective cohort study.
Participants: A total of 184 adults with TBI (72.
Studies of the negativity bias have demonstrated that negative information has a stronger influence than positive information in a wide range of cognitive domains. At odds with this literature is extensive work now documenting emotional and motivational shifts that result in a positivity effect in older adults. It remains unclear, however, whether this age-related positivity effect results from increases in processing of positive information or from decreases in processing of negative information.
View Article and Find Full Text PDFRotation rate and duration effects on the somatogyral illusion.
Aviat Space Environ Med
December 2006
Introduction: Aviation spatial disorientation mishaps remain a concern, especially due to their fatality rate. Some of the most insidious disorientations are due to vestibular stimuli in the absence of visual cues. A category of such disorientations are known as somatogyral illusions.
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