Publications by authors named "Christina Baumgarten"
Article Synopsis
- - Desmoid tumors (DT) are rare, locally aggressive sarcomas that often affect younger females (under 40), primarily causing high symptom burden and significant reductions in quality of life, despite having a good overall survival rate.
- - Common symptoms include pain, fatigue, and insomnia, with some patients experiencing disfigurement or mobility issues; anxiety and depression rates in DT patients can mirror those in more severe cancers.
- - The GOunder/Desmoid Tumor Research Foundation's DEsmoid Symptom/Impact Scale (GODDESS) evaluates patient-reported outcomes specific to DT, aiding in clinical trials to incorporate patient perspectives as new treatments are developed.
Objectives: The development of desmoid tumors (DT) is associated with trauma, which is an aspect with medicolegal relevance. The objective of this study was to analyze the proportion and type of trauma (surgical, blunt/fracture, implants), its lag time, and mutations of the CTNNB1 gene in patients with sporadic DT.
Methods: We analyzed a prospectively kept database of 381 females and 171 males, median age at disease onset 37.