Synopsis of recent research by authors named "Christina Battke"
- Christina Battke's research primarily focuses on the interactions between tumor cells and the immune system, particularly how tumor-derived factors impact immune cell function and contribute to immune evasion.
- Key findings include the discovery that tumor exosomes can inhibit the binding of tumor-reactive antibodies and induce apoptosis in T lymphocytes, highlighting the role of exosomes in creating an immunosuppressive tumor microenvironment.
- Battke has also characterized inhibitory antibodies targeting tumor-associated carbonic anhydrases, demonstrating their significance in regulating intracellular pH and facilitating tumor growth through metabolic processes crucial for glycolysis.