Impact of Education and Data Feedback on Guideline-Concordant Prescribing for Urinary Tract Infections in the Outpatient Setting.

Background: Urinary tract infections (UTIs) are the most common outpatient indication for antibiotics and an important target for antimicrobial stewardship (AS) activities. With The Joint Commission standards now requiring outpatient AS, data supporting effective strategies are needed.

Methods: We conducted a 2-phase, prospective, quasi-experimental study to estimate the effect of an outpatient AS intervention on guideline-concordant antibiotic prescribing in a primary care (PC) clinic and an urgent care (UC) clinic between August 2017 and July 2019.

Effectiveness of Vancomycin or Beta-Lactam Therapy in Ampicillin-Susceptible spp. Bloodstream Infections.

Background: De-escalation to a beta-lactam improves outcomes for patients with a methicillin-susceptible bloodstream infection (BSI). Whether a similar strategy is appropriate for enterococcal species is less clear.

Objective: To determine whether definitive antibiotic selection affects outcomes for patients with an ampicillin-susceptible enterococcal BSI.