Publications by authors named "Christie Y K Lung"

Active biomedical materials are designed to heal and restore the functions of people recovering after injuries or diseases [...

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Divalent cations have captured the interest of researchers in biomedical and dental fields due to their beneficial effects on bone formation. These metallic elements are similar to trace elements found in human bone. Strontium is a divalent cation commonly found in various biomaterials.

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Objectives: This study developed a sol-gel tricalcium silicate/graphene oxide (TCS-GO) composite and examined its physicochemical properties, antimicrobial activity, and osteo/odontogenic effect on dental pulp stem cells.

Methods: Tricalcium silicate was synthesized and combined with graphene oxide at three different concentrations, namely 0.02%, 0.

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Objective: This study aimed to examine the global research trend and frontiers in the field of root caries.

Methods: Two independent investigators searched the Web of Science Core Collection to include journal articles published on root caries from 1994 to 2023. They examined citation trends of the selected publications and performed bibliometric analysis using VOSviewer.

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Silver metal and compounds have antibacterial properties, although their action's mechanisms are not fully understood. Scientists generally consider that silver disrupts the bacterial cell wall. It causes a structural change in the bacterial cell membrane and cytoplasm.

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Ceramic nanomaterials are nanoscale inorganic metalloid solids that can be synthesised by heating at high temperatures followed by rapid cooling. Since the first nanoceramics were developed in the 1980s, ceramic nanomaterials have rapidly become one of the core nanomaterials for research because of their versatility in application and use in technology. Researchers are developing ceramic nanomaterials for dental use because ceramic nanoparticles are more stable and cheaper in production than metallic nanoparticles.

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Background: Non-metallic nanomaterials do not stain enamel or dentin. Most have better biocompatibility than metallic nanomaterials do for management of dental caries.

Objective: The objective of this study is to review the types, properties and potential uses of non-metallic nanomaterials systematically for managing dental caries.

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Graphene is a single-layer two-dimensional carbon-based nanomaterial. It presents as a thin and strong material that has attracted many researchers' attention. This study provides a concise review of the potential application of graphene materials in caries and periodontal disease management.

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Article Synopsis
  • - The study focused on creating a new biomaterial called calcium strontium silicate (CSR) to improve dental pulp therapies, emphasizing its ability to promote stem cell differentiation.
  • - CSR was synthesized and tested for its properties like pH, compressive strength, and bioactivity, with results indicating it outperformed calcium silicate (CS) in several aspects including faster setting times and higher cell viability.
  • - Enhanced differentiation of human dental pulp stem cells (HDPSC) was observed with CSR through increased alkaline phosphatase activity and greater mineralization over time compared to CS, suggesting CSR's potential for better clinical outcomes.
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Nanoparticles based on metal and metallic oxides have become a novel trend for dental applications. Metal nanoparticles are commonly used in dentistry for their exclusive shape-dependent properties, including their variable nano-sizes and forms, unique distribution, and large surface-area-to-volume ratio. These properties enhance the bio-physio-chemical functionalization, antimicrobial activity, and biocompatibility of the nanoparticles.

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Objectives: The objectives of the study were (1) to develop a novel multi-element-doped porous 58S bioactive glass coating for titanium implants and (2) to investigate the physiochemical, cell cytotoxic and antibacterial properties of this novel coating for titanium implants.

Methods: This study employed the sol-gel method to develop a silver-, cobalt (II) oxide- and titanium dioxide-doped 58S bioactive glass coating. The surface topography and in vitro bioactivity of the new bioactive glass-coated implants were studied using scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy.

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Zirconia (ZrO) ceramic is widely used in dentistry as a clinical dental biomaterial. In this review, we are focusing on and summarizing the biological performance of zirconia under different surface characteristics. We have included an initial tissue cell attachment study on zirconia and bacterial adhesion on zirconia.

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The aim of the current study was to synthesize a fast-setting ion-doped calcium silicate bioceramic by the sol-gel method and to characterize its in vitro apatite-forming ability and cell viability. Calcium silicate (CS), doped calcium silicate with zinc and magnesium, with Ca/Zn molar ratios of 6.7:1 (DCS1), and 4.

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Introduction: Pulp capping materials need to be able to protect the pulp but also bond to the overlying restorative materials. Light-curable pulp capping materials bond better to restorative materials and are easier to place than most water-based cements. The aim of this study was to characterize new light-curable tricalcium silicate-based pulp capping materials and compare their surface and antimicrobial properties with clinically available Theracal (Bisco, Schaumburg, IL) and Biodentine (Septodont, Saint-Maur-des-Fossés, France).

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Objective: To give a current review of silane adhesion chemistry, applications of silane coupling agents and related surface pretreatment methods in contemporary dentistry.

Methods: Silane coupling agents are adhesion promoters to chemically unify dissimilar materials used in dentistry. Silanes are very effective in adhesion promotion between resin composites and silica-based or silica-coated indirect restorative materials.

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Objectives: Characterization of a number of pulp capping materials and assessment of the leachate for elemental composition, antimicrobial activity and cell proliferation and expression.

Methodology: Three experimental light curable pulp-capping materials, Theracal and Biodentine were characterized by scanning electron microscopy, energy dispersive spectroscopy and X-ray diffraction. The elemental composition of the leachate formed after 24h was assessed by inductively coupled plasma (ICP).

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To evaluate the physical and mechanical properties of an experimental bis-GMA-based resin composite incorporated with non-silanized and silanized nano-hydroxyapatite (nHAP) fillers. Experimental bis-GMA based resin composites samples which were reinforced with nHAP fillers were prepared. Filler particles were surface treated with a silane coupling agent.

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In this study, the effect of silica coating on zirconia by silicon nitride hydrolysis in resin zirconia bonding was investigated. The silica coated zirconia samples were prepared in silicon nitride dispersion at 90 °C under different immersion times followed by a thermal treatment at 1400 °C. Four test groups were prepared: 1) zirconia samples treated by sandblasting, 2) zirconia samples treated by immersion in silicon nitride dispersion for 6 h, 3) zirconia samples treated by immersion in silicon nitride dispersion for 24 h and 4) zirconia samples treated by immersion in silicon nitride dispersion for 48 h.

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Purpose: To evaluate the in vitro effect of titanium surface treatment by a polydimethylsiloxane coating on the shear bond strength of a resin composite cement to titanium.

Materials And Methods: The titanium samples (40×30mm) were divided into 4 groups (n=12). A control group was surface treated by sandblasting using 110µm silica-coated alumina powder at a constant pressure of 300kPa for 15s/1cm(2).

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Objectives: To investigate the effect of eicosapentaenoic acid (EPA)-coated Ti implants on osteoconduction in white New Zealand rabbit mandibles.

Material And Methods: Sandblasted and cleansed planar titanium specimens with a size of 5 × 5 × 1 mm were coated on one side with 0.25 vol% eicosapentaenoic acid (EPA).

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The effect of silica-coating by sol-gel process on the bond strength of resin composite to zirconia was evaluated and compared against the sandblasting method. Four groups of zirconia samples were silica-coated by sol-gel process under varied reagent ratios of ethanol, water, ammonia and tetraethyl orthosilicate and for different deposition times. One control group of zirconia samples were treated with sandblasting.

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Objectives: To evaluate and compare three novel coupling agents: 2-hydroxyethyl methacrylate, itaconic acid and oleic acid to two silane coupling agents, one commercial silane product and 3-acryloxypropyltrimethoxysilane on the bond durability of resin composite to zirconia.

Methods: Zirconia samples were silica-coated by air abrasion and each of the five coupling agents was then applied to give five test groups. Resin composite stubs were bonded onto the conditioned zirconia surfaces.

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Objectives: To give an overview of aspects of silane coupling agents and surface conditioning in dentistry.

Methods: Currently, silane coupling agents are used as adhesion promoters. Silanes are effective in enhancing adhesion between resin composite and silica-based ceramics.

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Objective: To study in vitro the effect of two cross-linking silanes, bis-1,2-(triethoxysilyl)ethane and bis[3-(trimethoxysilyl)propyl]amine, blended with an organofunctional silane coupling agent, (3-acryloxypropyl)trimethoxysilane, on the shear bond strength between resin-composite cement and silicatized zirconia after dry storage and thermocycling.

Materials And Methods: Six tested groups of 90 samples of yttria stabilized zirconia were used for sample preparation. The surfaces of the zirconia were silica-coated.

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Gas chromatography (GC) was investigated for the determination of residual methyl methacrylate (MMA) in heat-processed poly(methyl methacrylate) (PMMA) denture base material emphasizing recovery and validation. Standard solutions of MMA and emulsion-polymerized PMMA in dichloromethane were analysed, before and after distillation by a room-temperature air stream into a liquid nitrogen trap, and in the presence of PMMA by direct injection. Quantitative NMR analysis using dimethyl sulphoxide as internal calibration standard in deuterated chloroform solutions provided validation.

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