Publications by authors named "Christie Arrasate"
Analysis of chronic obstructive pulmonary disease exacerbations with the dual bronchodilator QVA149 compared with glycopyrronium and tiotropium (SPARK): a randomised, double-blind, parallel-group study.
Jadwiga A Wedzicha Marc Decramer Joachim H Ficker Dennis E Niewoehner Thomas Sandström Christie Arrasate
Lancet Respir Med
May 2013
Article Synopsis
- A study investigated how a dual long-acting inhaled bronchodilator, QVA149, affects exacerbations in severe COPD patients compared to other treatments.
- Researchers assigned 2224 patients into three groups receiving QVA149, glycopyrronium, or tiotropium over 64 weeks, with a focus on comparing rates of moderate to severe exacerbations.
- Results showed that QVA149 reduced exacerbation rates by 12% compared to glycopyrronium, while the safety profile was similar across all treatments, with most patients experiencing adverse events.