Publications by authors named "Christiane Schlegel"
Background: Infections are a major cause for morbidity and mortality in neonates; however, the underling mechanisms for increased infection susceptibility are incompletely understood. Hypoxia, which is present in inflamed tissues, has been identified as an important activation signal for innate immune cells in adults and is mainly mediated by hypoxia-inducible factor 1α (HIF-1α). Fetal tissue pO physiologically is low but rises immediately after birth.
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- The airborne SARS-CoV-2 virus significantly threatens the elderly and those with pre-existing conditions, particularly in South German nursing homes, prompting urgent preventive measures by the government.
- A study in Reutlingen County details a three-phase COVID-19 testing strategy, involving extensive testing of residents and staff, contact tracing, isolation, and hygiene inspections to manage outbreaks.
- Results showed high testing rates (98% of residents, 92% of staff), with a notable number of cases discovered in nursing homes, leading to effective early interventions and changes in German legislation, suggesting that these outbreak management strategies could be beneficial in other countries as well.
Progressive mucinous histiocytosis is a very rare, benign, non-Langerhans' cell histiocytosis limited to the skin. In total ten patients (all women) in four families and three sporadic cases have been reported. We report here the first published case of a male patient with progressive mucinous histiocytosis.
View Article and Find Full Text PDFEmergency sets are prescribed to allow patients with anaphylaxis to treat themselves before professional aid arrives. The need for epinephrine in this setting is well-accepted, but how it should be administered is still controversial. Epinephrine preparations can be administered orally, subcutaneously, intramuscularly or as aerosols.
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