Publications by authors named "Christiane Romain"
Article Synopsis
- Organophosphorus (OP) compounds are a significant global public health issue, causing millions of poisonings and over 200,000 deaths annually due to their severe effects on the nervous system.
- Using a zebrafish model, researchers demonstrated that diisopropylfluorophosphate (DFP), a toxic OP, leads to enzyme inhibition, paralysis, neuron overactivity, increased apoptosis, and potential long-term cognitive damage.
- The study found that DFP exposure alters the balance of synaptic activity in neurons, which suggests that the zebrafish model can help deepen understanding of OP toxicity and aid in finding new antidotes.
