Publications by authors named "Christiane Mhanna"
Article Synopsis
- The study examines the effects of postnatal steroid treatment on the severity of retinopathy of prematurity (ROP) and its impact on how quickly the retina develops in premature infants born at ≤32 weeks gestation or weighing ≤1500 g.
- Out of 1695 infants analyzed, 67% received steroid therapy, revealing that higher doses and longer treatment durations significantly increased the incidence of severe ROP and delayed full vascularization of the retina.
- The findings suggest that the use of postnatal steroids needs to be carefully considered, as they are linked to worse ROP outcomes and slower retinal development in vulnerable infants.
Background: Preterm neonates often require glucocorticoids to manage refractory hypotension, prevent, and treat bronchopulmonary dysplasia. We have investigated the effect of cumulative dose and duration of glucocorticoids on blood pressure and renal function in VLBW infants.
Methods: In this retrospective cohort study, medical records of infants (GA ≤ 35 weeks) born January 2015 to December 2019 were reviewed to extract demographic and clinical characteristics, dose and duration of steroids, blood pressure (BP), and creatinine at the time of discharge from the neonatal intensive care unit.
Renal cystic lesions are considered the most common abnormality associated with the kidneys. Most renal cysts are usually uncomplicated simple cysts that are not life-threatening; however, fatal renal cystic diseases can develop from these space-occupying lesions. Although renal cystic diseases are similar in presentation, they possess distinct features, variable prognoses, and complications later in life.
View Article and Find Full Text PDFThe transverse carpal ligament (TCL) plays a critical role in carpal tunnel biomechanics through interactions with its surrounding tissues. The purpose of this study was to investigate the in vivo adaptations of the TCL's mechanical properties in response to repetitive hand use in pianists using acoustic radiation force impulse (ARFI) imaging. It was hypothesized that pianists, in comparison to non-pianists, would have a stiffer TCL as indicated by an increased acoustic shear wave velocity (SWV).
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